CHRDL1 | OmnibusX

Name	Number of supported studies	Average coverage
endothelial cell of lymphatic vessel	12 studies	27% ± 11%	Explore
fibroblast	10 studies	33% ± 14%	Explore
adventitial cell	4 studies	32% ± 16%	Explore
Mueller cell	4 studies	30% ± 15%	Explore
astrocyte	4 studies	36% ± 11%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CHRDL1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	89%	9759.93	219 / 245	97%	57.47	485 / 502
breast	99%	11836.54	456 / 459	60%	15.38	674 / 1118
lung	99%	12268.90	575 / 578	58%	12.80	674 / 1155
thymus	96%	6668.36	630 / 653	42%	8.45	252 / 605
brain	46%	1650.29	1225 / 2642	87%	31.46	613 / 705
intestine	86%	8173.78	828 / 966	35%	7.56	182 / 527
uterus	96%	14203.62	163 / 170	24%	20.70	109 / 459
esophagus	82%	9071.91	1192 / 1445	33%	8.77	61 / 183
bladder	81%	3018.57	17 / 21	27%	5.54	136 / 504
adipose	100%	17671.13	1204 / 1204	0%	0	0 / 0
blood vessel	83%	6507.38	1107 / 1335	0%	0	0 / 0
skin	42%	1661.16	762 / 1809	38%	20.59	179 / 472
stomach	38%	2194.32	135 / 359	38%	7.69	110 / 286
kidney	45%	1439.58	40 / 89	24%	7.41	216 / 901
pancreas	3%	57.38	9 / 328	62%	19.73	110 / 178
spleen	63%	2480.51	153 / 241	0%	0	0 / 0
ovary	12%	871.13	21 / 180	50%	8.79	217 / 430
lymph node	0%	0	0 / 0	38%	2.74	11 / 29
heart	33%	1218.93	287 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	31%	3.68	14 / 45
adrenal gland	5%	113.66	12 / 258	7%	0.64	15 / 230
eye	0%	0	0 / 0	10%	1.36	8 / 80
liver	0%	0	0 / 226	8%	1.09	33 / 406
muscle	6%	164.92	48 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0030509	Biological process	BMP signaling pathway
GO_0048167	Biological process	regulation of synaptic plasticity
GO_0001503	Biological process	ossification
GO_0098976	Biological process	excitatory chemical synaptic transmission
GO_0030154	Biological process	cell differentiation
GO_0030514	Biological process	negative regulation of BMP signaling pathway
GO_0060074	Biological process	synapse maturation
GO_0001654	Biological process	eye development
GO_0000578	Biological process	embryonic axis specification
GO_0097113	Biological process	AMPA glutamate receptor clustering
GO_0005788	Cellular component	endoplasmic reticulum lumen
GO_0005576	Cellular component	extracellular region
GO_0045202	Cellular component	synapse
GO_0005886	Cellular component	plasma membrane
GO_0050431	Molecular function	transforming growth factor beta binding
GO_0036122	Molecular function	BMP binding

Gene name	CHRDL1
Protein name	Chordin-like protein 1 (Neuralin-1) (Neurogenesin-1) (Ventroptin) Chordin like 1
Synonyms	NRLN1
Description	FUNCTION: Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation (By similarity). May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development. .
Accessions	Q9BU40 A0A452Q6Z9 ENST00000482160.5 [Q9BU40-3] ENST00000444321.2 [Q9BU40-5] ENST00000394797.8 [Q9BU40-6] ENST00000372045.5 ENST00000372042.6 [Q9BU40-4]

CHRDL1 report