CALR3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CALR3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CALR3 at tissue level.

III. Associated gene sets

GO_0006457Biological processprotein folding
GO_0007283Biological processspermatogenesis
GO_0030154Biological processcell differentiation
GO_0008150Biological processbiological_process
GO_0036503Biological processERAD pathway
GO_0005788Cellular componentendoplasmic reticulum lumen
GO_0005635Cellular componentnuclear envelope
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0044183Molecular functionprotein folding chaperone
GO_0051082Molecular functionunfolded protein binding
GO_0005509Molecular functioncalcium ion binding
GO_0030246Molecular functioncarbohydrate binding

IV. Literature review

[source]
Gene nameCALR3
Protein nameCalreticulin 3
Calreticulin-3 (Calreticulin-2) (Calsperin)
SynonymsCRT2
DescriptionFUNCTION: During spermatogenesis, may act as a lectin-independent chaperone for specific client proteins such as ADAM3. Required for sperm fertility (By similarity). CALR3 capacity for calcium-binding may be absent or much lower than that of CALR. .

AccessionsA0A7R6RQ58
ENST00000600762.1
Q96L12
M0R0Y8
ENST00000269881.8