Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 31 studies | 56% ± 23% | |
| fibroblast | 23 studies | 44% ± 22% | |
| macrophage | 23 studies | 47% ± 27% | |
| astrocyte | 20 studies | 59% ± 18% | |
| pericyte | 17 studies | 43% ± 23% | |
| oligodendrocyte | 16 studies | 79% ± 19% | |
| oligodendrocyte precursor cell | 16 studies | 72% ± 18% | |
| microglial cell | 16 studies | 74% ± 13% | |
| smooth muscle cell | 13 studies | 48% ± 18% | |
| glutamatergic neuron | 12 studies | 50% ± 22% | |
| GABAergic neuron | 11 studies | 66% ± 21% | |
| endothelial cell of lymphatic vessel | 10 studies | 50% ± 22% | |
| myofibroblast cell | 9 studies | 35% ± 22% | |
| epithelial cell | 9 studies | 45% ± 20% | |
| myeloid cell | 9 studies | 49% ± 24% | |
| adipocyte | 9 studies | 60% ± 17% | |
| mast cell | 9 studies | 40% ± 17% | |
| T cell | 8 studies | 37% ± 14% | |
| neuron | 8 studies | 52% ± 29% | |
| mesothelial cell | 8 studies | 48% ± 17% | |
| interneuron | 7 studies | 64% ± 23% | |
| capillary endothelial cell | 7 studies | 34% ± 20% | |
| dendritic cell | 7 studies | 45% ± 14% | |
| ciliated cell | 7 studies | 35% ± 18% | |
| abnormal cell | 6 studies | 30% ± 21% | |
| vein endothelial cell | 6 studies | 49% ± 27% | |
| connective tissue cell | 6 studies | 34% ± 21% | |
| basal cell | 6 studies | 53% ± 25% | |
| natural killer cell | 6 studies | 31% ± 13% | |
| progenitor cell | 5 studies | 47% ± 26% | |
| glial cell | 5 studies | 49% ± 19% | |
| B cell | 5 studies | 45% ± 13% | |
| CD4-positive, alpha-beta T cell | 5 studies | 32% ± 8% | |
| cardiac muscle cell | 5 studies | 56% ± 16% | |
| endothelial cell of artery | 5 studies | 40% ± 18% | |
| retinal cone cell | 5 studies | 63% ± 28% | |
| monocyte | 5 studies | 57% ± 8% | |
| club cell | 5 studies | 51% ± 20% | |
| type I pneumocyte | 5 studies | 62% ± 10% | |
| type II pneumocyte | 5 studies | 55% ± 9% | |
| regulatory T cell | 5 studies | 30% ± 10% | |
| cholangiocyte | 4 studies | 62% ± 20% | |
| hepatocyte | 4 studies | 63% ± 28% | |
| granule cell | 4 studies | 57% ± 16% | |
| plasma cell | 4 studies | 41% ± 11% | |
| CD8-positive, alpha-beta T cell | 4 studies | 32% ± 6% | |
| lymphocyte | 4 studies | 42% ± 18% | |
| Mueller cell | 4 studies | 64% ± 24% | |
| amacrine cell | 4 studies | 45% ± 14% | |
| retina horizontal cell | 4 studies | 45% ± 22% | |
| retinal rod cell | 4 studies | 63% ± 17% | |
| endothelial cell of vascular tree | 4 studies | 54% ± 26% | |
| leukocyte | 4 studies | 69% ± 7% | |
| naive B cell | 4 studies | 17% ± 1% | |
| endothelial cell of sinusoid | 3 studies | 38% ± 9% | |
| hepatic stellate cell | 3 studies | 56% ± 21% | |
| renal alpha-intercalated cell | 3 studies | 44% ± 16% | |
| renal beta-intercalated cell | 3 studies | 50% ± 18% | |
| differentiation-committed oligodendrocyte precursor | 3 studies | 80% ± 1% | |
| interstitial cell of Cajal | 3 studies | 35% ± 19% | |
| neural crest cell | 3 studies | 31% ± 3% | |
| GABAergic interneuron | 3 studies | 65% ± 5% | |
| precursor B cell | 3 studies | 21% ± 3% | |
| effector memory CD8-positive, alpha-beta T cell | 3 studies | 32% ± 12% | |
| mononuclear phagocyte | 3 studies | 51% ± 21% | |
| mucosal invariant T cell | 3 studies | 26% ± 9% | |
| non-classical monocyte | 3 studies | 22% ± 8% | |
| GABAergic amacrine cell | 3 studies | 54% ± 17% | |
| glycinergic amacrine cell | 3 studies | 58% ± 18% | |
| retinal ganglion cell | 3 studies | 54% ± 19% | |
| retinal pigment epithelial cell | 3 studies | 54% ± 24% | |
| ependymal cell | 3 studies | 71% ± 12% | |
| adventitial cell | 3 studies | 37% ± 18% | |
| alveolar macrophage | 3 studies | 66% ± 10% | |
| chondrocyte | 3 studies | 44% ± 18% | |
| respiratory goblet cell | 3 studies | 59% ± 19% | |
| muscle cell | 3 studies | 52% ± 25% | |
| goblet cell | 3 studies | 43% ± 33% | |
| brush cell | 3 studies | 26% ± 8% | |
| mucus secreting cell | 3 studies | 56% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 4391.61 | 1445 / 1445 | 100% | 43.92 | 183 / 183 |
| brain | 100% | 3190.22 | 2641 / 2642 | 100% | 166.85 | 705 / 705 |
| lung | 100% | 4385.60 | 578 / 578 | 99% | 27.31 | 1143 / 1155 |
| intestine | 100% | 4064.65 | 966 / 966 | 98% | 30.77 | 519 / 527 |
| breast | 100% | 4916.16 | 459 / 459 | 98% | 36.32 | 1098 / 1118 |
| ovary | 100% | 5316.49 | 180 / 180 | 98% | 22.90 | 421 / 430 |
| thymus | 100% | 4082.33 | 653 / 653 | 98% | 29.41 | 591 / 605 |
| stomach | 100% | 3519.78 | 359 / 359 | 98% | 35.54 | 279 / 286 |
| prostate | 100% | 4591.67 | 245 / 245 | 97% | 26.96 | 485 / 502 |
| pancreas | 98% | 1569.78 | 320 / 328 | 97% | 25.17 | 173 / 178 |
| bladder | 100% | 5697.67 | 21 / 21 | 95% | 22.23 | 477 / 504 |
| uterus | 100% | 6207.80 | 170 / 170 | 94% | 24.80 | 431 / 459 |
| kidney | 100% | 2899.07 | 89 / 89 | 94% | 25.83 | 843 / 901 |
| skin | 100% | 5306.08 | 1808 / 1809 | 93% | 39.69 | 441 / 472 |
| adrenal gland | 100% | 3279.24 | 258 / 258 | 86% | 13.84 | 198 / 230 |
| liver | 100% | 1539.40 | 226 / 226 | 65% | 10.24 | 265 / 406 |
| adipose | 100% | 5145.88 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 4979.73 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 100% | 2737.52 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 7.48 | 1 / 1 |
| muscle | 100% | 2509.64 | 801 / 803 | 0% | 0 | 0 / 0 |
| heart | 98% | 2285.43 | 845 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 89% | 19.75 | 40 / 45 |
| eye | 0% | 0 | 0 / 0 | 83% | 24.58 | 66 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 62% | 11.73 | 18 / 29 |
| peripheral blood | 55% | 1613.93 | 511 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0010628 | Biological process | positive regulation of gene expression |
| GO_0097210 | Biological process | response to gonadotropin-releasing hormone |
| GO_0006955 | Biological process | immune response |
| GO_0030154 | Biological process | cell differentiation |
| GO_0007517 | Biological process | muscle organ development |
| GO_0010467 | Biological process | gene expression |
| GO_0045666 | Biological process | positive regulation of neuron differentiation |
| GO_0007399 | Biological process | nervous system development |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0016607 | Cellular component | nuclear speck |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0090575 | Cellular component | RNA polymerase II transcription regulator complex |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0000785 | Cellular component | chromatin |
| GO_0005667 | Cellular component | transcription regulator complex |
| GO_0005634 | Cellular component | nucleus |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0140297 | Molecular function | DNA-binding transcription factor binding |
| GO_0043425 | Molecular function | bHLH transcription factor binding |
| GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0000987 | Molecular function | cis-regulatory region sequence-specific DNA binding |
| GO_0000976 | Molecular function | transcription cis-regulatory region binding |
| GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
| GO_0046332 | Molecular function | SMAD binding |
| GO_0003700 | Molecular function | DNA-binding transcription factor activity |
| GO_0046982 | Molecular function | protein heterodimerization activity |
| GO_0070888 | Molecular function | E-box binding |
| GO_0035497 | Molecular function | cAMP response element binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0071837 | Molecular function | HMG box domain binding |
| Gene name | TCF12 |
| Protein name | Transcription factor 12 Transcription factor 12 (DNA-binding protein HTF4) (E-box-binding protein) (Transcription factor HTF-4) Transcription factor 12 (TCF-12) (Class B basic helix-loop-helix protein 20) (bHLHb20) (DNA-binding protein HTF4) (E-box-binding protein) (Transcription factor HTF-4) |
| Synonyms | BHLHB20 HTF4 HEB |
| Description | FUNCTION: Transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3') (By similarity). May be involved in the functional network that regulates the development of the GnRH axis . . |
| Accessions | B4DZP2 B4DGI9 ENST00000537840.5 [Q99081-4] ENST00000267811.9 [Q99081-1] ENST00000333725.10 [Q99081-3] ENST00000438423.6 [Q99081-3] ENST00000561152.1 ENST00000559710.5 Q99081 ENST00000559609.5 Q9NQY1 ENST00000560948.1 ENST00000559703.1 H3BNF4 ENST00000557843.5 [Q99081-1] Q9NQY4 ENST00000543579.5 ENST00000343827.7 [Q99081-2] Q9NQY5 ENST00000557947.5 H0YML2 Q9NQY8 H3BRK2 Q9NQY9 H0YNP8 Q9NQY2 H0YNQ5 Q9NQY7 Q9NQY3 Q9NQY6 ENST00000560836.1 F5GY10 |