TCF12 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0010628Biological processpositive regulation of gene expression
GO_0097210Biological processresponse to gonadotropin-releasing hormone
GO_0006955Biological processimmune response
GO_0030154Biological processcell differentiation
GO_0007517Biological processmuscle organ development
GO_0010467Biological processgene expression
GO_0045666Biological processpositive regulation of neuron differentiation
GO_0007399Biological processnervous system development
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0016607Cellular componentnuclear speck
GO_0005654Cellular componentnucleoplasm
GO_0090575Cellular componentRNA polymerase II transcription regulator complex
GO_0005737Cellular componentcytoplasm
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0000785Cellular componentchromatin
GO_0005667Cellular componenttranscription regulator complex
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0140297Molecular functionDNA-binding transcription factor binding
GO_0043425Molecular functionbHLH transcription factor binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0000987Molecular functioncis-regulatory region sequence-specific DNA binding
GO_0000976Molecular functiontranscription cis-regulatory region binding
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0046332Molecular functionSMAD binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0046982Molecular functionprotein heterodimerization activity
GO_0070888Molecular functionE-box binding
GO_0035497Molecular functioncAMP response element binding
GO_0005515Molecular functionprotein binding
GO_0071837Molecular functionHMG box domain binding

IV. Literature review

[source]
Gene nameTCF12
Protein nameTranscription factor 12
Transcription factor 12 (DNA-binding protein HTF4) (E-box-binding protein) (Transcription factor HTF-4)
Transcription factor 12 (TCF-12) (Class B basic helix-loop-helix protein 20) (bHLHb20) (DNA-binding protein HTF4) (E-box-binding protein) (Transcription factor HTF-4)
SynonymsBHLHB20
HTF4
HEB
DescriptionFUNCTION: Transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3') (By similarity). May be involved in the functional network that regulates the development of the GnRH axis . .

AccessionsB4DZP2
B4DGI9
ENST00000537840.5 [Q99081-4]
ENST00000267811.9 [Q99081-1]
ENST00000333725.10 [Q99081-3]
ENST00000438423.6 [Q99081-3]
ENST00000561152.1
ENST00000559710.5
Q99081
ENST00000559609.5
Q9NQY1
ENST00000560948.1
ENST00000559703.1
H3BNF4
ENST00000557843.5 [Q99081-1]
Q9NQY4
ENST00000543579.5
ENST00000343827.7 [Q99081-2]
Q9NQY5
ENST00000557947.5
H0YML2
Q9NQY8
H3BRK2
Q9NQY9
H0YNP8
Q9NQY2
H0YNQ5
Q9NQY7
Q9NQY3
Q9NQY6
ENST00000560836.1
F5GY10