RBM38 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0043484Biological processregulation of RNA splicing
GO_0008380Biological processRNA splicing
GO_0006397Biological processmRNA processing
GO_0030154Biological processcell differentiation
GO_0010830Biological processregulation of myotube differentiation
GO_0005829Cellular componentcytosol
GO_0005634Cellular componentnucleus
GO_0003730Molecular functionmRNA 3'-UTR binding
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameRBM38
Protein nameRNA-binding protein 38 (CLL-associated antigen KW-5) (HSRNASEB) (RNA-binding motif protein 38) (RNA-binding region-containing protein 1) (ssDNA-binding protein SEB4)
RNA-binding protein 38 (RNA-binding motif protein 38)
RNA binding motif protein 38
SynonymsSEB4
RNPC1
DescriptionFUNCTION: RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation. .; FUNCTION: (Microbial infection) Essential factor for the splicing of the pre-mRNAs of human parvovirus B19 (B19V) and for the expression of B19V 11-kDa protein, which enhances viral replication. .

AccessionsENST00000342690.4
ENST00000356208.10 [Q9H0Z9-1]
ENST00000371219.2
ENST00000440234.6 [Q9H0Z9-2]
ENST00000344785.10
F6VZ39
Q9H0Z9
A6NG75
E9PSF1