I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| pericyte | 14 studies | 61% ± 28% | |
| fibroblast | 11 studies | 40% ± 28% | |
| smooth muscle cell | 8 studies | 45% ± 25% | |
| connective tissue cell | 3 studies | 24% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| pericyte | 14 studies | 61% ± 28% | |
| fibroblast | 11 studies | 40% ± 28% | |
| smooth muscle cell | 8 studies | 45% ± 25% | |
| connective tissue cell | 3 studies | 24% ± 4% |
Insufficient scRNA-seq data for expression of EGFL6 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 2874.24 | 577 / 578 | 91% | 29.02 | 1051 / 1155 |
| bladder | 90% | 219.38 | 19 / 21 | 81% | 11.30 | 408 / 504 |
| esophagus | 47% | 177.13 | 676 / 1445 | 91% | 18.73 | 166 / 183 |
| breast | 74% | 375.80 | 340 / 459 | 57% | 6.90 | 638 / 1118 |
| stomach | 50% | 50.58 | 179 / 359 | 59% | 4.97 | 168 / 286 |
| uterus | 29% | 40.39 | 50 / 170 | 78% | 22.20 | 359 / 459 |
| ovary | 7% | 7.57 | 12 / 180 | 97% | 33.14 | 418 / 430 |
| ureter | 0% | 0 | 0 / 0 | 100% | 5.75 | 1 / 1 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 14.36 | 43 / 45 |
| adipose | 81% | 1524.00 | 971 / 1204 | 0% | 0 | 0 / 0 |
| intestine | 6% | 9.53 | 62 / 966 | 60% | 4.88 | 316 / 527 |
| pancreas | 0% | 0.15 | 1 / 328 | 62% | 5.49 | 111 / 178 |
| skin | 33% | 50.32 | 606 / 1809 | 22% | 1.67 | 102 / 472 |
| thymus | 31% | 33.04 | 203 / 653 | 15% | 3.86 | 92 / 605 |
| lymph node | 0% | 0 | 0 / 0 | 41% | 5.89 | 12 / 29 |
| prostate | 36% | 68.56 | 88 / 245 | 1% | 0.09 | 7 / 502 |
| brain | 20% | 21.38 | 528 / 2642 | 4% | 0.30 | 30 / 705 |
| kidney | 6% | 3.96 | 5 / 89 | 6% | 1.97 | 55 / 901 |
| blood vessel | 8% | 9.98 | 105 / 1335 | 0% | 0 | 0 / 0 |
| liver | 0% | 0 | 0 / 226 | 4% | 0.18 | 16 / 406 |
| adrenal gland | 0% | 0.21 | 1 / 258 | 3% | 0.43 | 6 / 230 |
| peripheral blood | 3% | 4.82 | 25 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.28 | 2 / 80 |
| muscle | 1% | 1.45 | 10 / 803 | 0% | 0 | 0 / 0 |
| spleen | 1% | 0.71 | 3 / 241 | 0% | 0 | 0 / 0 |
| heart | 1% | 1.43 | 7 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0030198 | Biological process | extracellular matrix organization |
| GO_0007155 | Biological process | cell adhesion |
| GO_0030154 | Biological process | cell differentiation |
| GO_0010811 | Biological process | positive regulation of cell-substrate adhesion |
| GO_0005604 | Cellular component | basement membrane |
| GO_0005615 | Cellular component | extracellular space |
| GO_0016020 | Cellular component | membrane |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0005178 | Molecular function | integrin binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | EGFL6 |
| Protein name | Epidermal growth factor-like protein 6 (EGF-like protein 6) (MAM and EGF domains-containing gene protein) |
| Synonyms | PP648 MAEG UNQ281/PRO320 |
| Description | FUNCTION: May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly (By similarity). . |
| Accessions | Q8IUX8 ENST00000380602.3 [Q8IUX8-2] ENST00000361306.6 [Q8IUX8-1] |
