TXNDC8 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TXNDC8 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TXNDC8 at tissue level.

III. Associated gene sets

GO_0007283Biological processspermatogenesis
GO_0030154Biological processcell differentiation
GO_0070062Cellular componentextracellular exosome
GO_0001669Cellular componentacrosomal vesicle
GO_0005794Cellular componentGolgi apparatus
GO_0005737Cellular componentcytoplasm
GO_0015035Molecular functionprotein-disulfide reductase activity

IV. Literature review

[source]
Gene nameTXNDC8
Protein nameThioredoxin domain containing 8
Thioredoxin domain-containing protein 8 (Spermatid-specific thioredoxin-3) (Sptrx-3) (Thioredoxin-6)
TXNDC8 protein (Thioredoxin domain containing 8)
SynonymsSPTRX3
TRX6
hCG_1994624
DescriptionFUNCTION: May be required for post-translational modifications of proteins required for acrosomal biogenesis. May act by reducing disulfide bonds within the sperm.

AccessionsENST00000374511.7 [Q6A555-1]
Q6A555
ENST00000374507.4
B7ZME0
ENST00000423740.7
ENST00000374510.8 [Q6A555-2]
A9Z1W9