HTATIP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0001525Biological processangiogenesis
GO_0051170Biological processimport into nucleus
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0045765Biological processregulation of angiogenesis
GO_0043066Biological processnegative regulation of apoptotic process
GO_0043068Biological processpositive regulation of programmed cell death
GO_0030154Biological processcell differentiation
GO_0006915Biological processapoptotic process
GO_0046777Biological processprotein autophosphorylation
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0016020Cellular componentmembrane
GO_0005635Cellular componentnuclear envelope
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0004674Molecular functionprotein serine/threonine kinase activity
GO_0016491Molecular functionoxidoreductase activity
GO_0003713Molecular functiontranscription coactivator activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameHTATIP2
Protein nameOxidoreductase HTATIP2 (EC 1.1.1.-) (30 kDa HIV-1 TAT-interacting protein) (HIV-1 TAT-interactive protein 2)
Oxidoreductase HTATIP2
SynonymsTIP30
CC3
DescriptionFUNCTION: Oxidoreductase required for tumor suppression. NADPH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect. .

AccessionsENST00000419348.6 [Q9BUP3-3]
ENST00000443524.6 [Q9BUP3-1]
ENST00000532505.1 [Q9BUP3-2]
ENST00000530266.5 [Q9BUP3-2]
Q9BUP3
ENST00000531058.1
ENST00000451739.7 [Q9BUP3-1]
ENST00000421577.6 [Q9BUP3-1]
ENST00000532081.1 [Q9BUP3-2]
E9PI87