Name | Number of supported studies | Average coverage | |
---|---|---|---|
classical monocyte | 12 studies | 26% ± 11% | |
fibroblast | 9 studies | 18% ± 3% | |
adipocyte | 9 studies | 37% ± 8% | |
alveolar macrophage | 8 studies | 36% ± 15% | |
neutrophil | 8 studies | 33% ± 20% | |
endothelial cell | 8 studies | 19% ± 4% | |
macrophage | 7 studies | 20% ± 6% | |
non-classical monocyte | 7 studies | 23% ± 8% | |
epithelial cell | 5 studies | 34% ± 15% | |
basal cell | 5 studies | 21% ± 3% | |
squamous epithelial cell | 4 studies | 44% ± 21% | |
myeloid cell | 4 studies | 19% ± 4% | |
monocyte | 4 studies | 33% ± 17% | |
luminal hormone-sensing cell of mammary gland | 3 studies | 24% ± 8% | |
pericyte | 3 studies | 24% ± 8% | |
GABAergic neuron | 3 studies | 35% ± 4% | |
glutamatergic neuron | 3 studies | 43% ± 5% | |
oligodendrocyte | 3 studies | 24% ± 3% | |
astrocyte | 3 studies | 17% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 2194.95 | 459 / 459 | 100% | 19.33 | 1116 / 1118 |
bladder | 100% | 1042.19 | 21 / 21 | 100% | 15.50 | 503 / 504 |
lung | 99% | 1408.06 | 574 / 578 | 100% | 12.84 | 1154 / 1155 |
thymus | 100% | 855.89 | 651 / 653 | 100% | 13.48 | 602 / 605 |
skin | 100% | 2389.47 | 1809 / 1809 | 97% | 9.41 | 457 / 472 |
esophagus | 97% | 1393.71 | 1399 / 1445 | 100% | 12.84 | 183 / 183 |
kidney | 100% | 747.16 | 89 / 89 | 96% | 8.55 | 863 / 901 |
intestine | 95% | 670.27 | 916 / 966 | 98% | 9.04 | 518 / 527 |
stomach | 93% | 751.07 | 335 / 359 | 99% | 9.42 | 282 / 286 |
prostate | 91% | 575.71 | 222 / 245 | 100% | 10.52 | 500 / 502 |
liver | 90% | 559.46 | 204 / 226 | 96% | 7.39 | 388 / 406 |
adrenal gland | 95% | 935.23 | 245 / 258 | 87% | 5.75 | 200 / 230 |
pancreas | 83% | 702.73 | 271 / 328 | 99% | 10.88 | 176 / 178 |
uterus | 69% | 322.12 | 117 / 170 | 100% | 16.91 | 458 / 459 |
brain | 65% | 354.17 | 1710 / 2642 | 100% | 17.74 | 704 / 705 |
ovary | 59% | 269.12 | 106 / 180 | 99% | 8.70 | 424 / 430 |
tonsil | 0% | 0 | 0 / 0 | 100% | 15.84 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 22.50 | 1 / 1 |
adipose | 100% | 2674.47 | 1203 / 1204 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 4064.39 | 921 / 929 | 0% | 0 | 0 / 0 |
spleen | 99% | 787.17 | 238 / 241 | 0% | 0 | 0 / 0 |
muscle | 93% | 659.35 | 749 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 90% | 608.55 | 1196 / 1335 | 0% | 0 | 0 / 0 |
heart | 84% | 617.70 | 720 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 79% | 5.45 | 23 / 29 |
eye | 0% | 0 | 0 / 0 | 35% | 1.38 | 28 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006654 | Biological process | phosphatidic acid biosynthetic process |
GO_0055088 | Biological process | lipid homeostasis |
GO_0010898 | Biological process | positive regulation of triglyceride catabolic process |
GO_0030154 | Biological process | cell differentiation |
GO_0010891 | Biological process | negative regulation of sequestering of triglyceride |
GO_0006631 | Biological process | fatty acid metabolic process |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005811 | Cellular component | lipid droplet |
GO_0005739 | Cellular component | mitochondrion |
GO_0004806 | Molecular function | triglyceride lipase activity |
GO_0003841 | Molecular function | 1-acylglycerol-3-phosphate O-acyltransferase activity |
GO_0060229 | Molecular function | lipase activator activity |
GO_0005515 | Molecular function | protein binding |
GO_0052689 | Molecular function | carboxylic ester hydrolase activity |
GO_0042171 | Molecular function | lysophosphatidic acid acyltransferase activity |
Gene name | ABHD5 |
Protein name | 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (EC 2.3.1.51) (Abhydrolase domain-containing protein 5) (Lipid droplet-binding protein CGI-58) Abhydrolase domain containing protein 5 (EC 2.3.1.51) Abhydrolase domain containing 5 (EC 2.3.1.51) 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (EC 2.3.1.51) (Abhydrolase domain-containing protein 5) Truncated abhydrolase domain containing 5 (EC 2.3.1.51) Abhydrolase domain containing 5, lysophosphatidic acid acyltransferase Truncated abhydrolase domain-containing protein 5 (EC 2.3.1.51) |
Synonyms | NCIE2 CGI-58 |
Description | FUNCTION: Coenzyme A-dependent lysophosphatidic acid acyltransferase that catalyzes the transfer of an acyl group on a lysophosphatidic acid . Functions preferentially with 1-oleoyl-lysophosphatidic acid followed by 1-palmitoyl-lysophosphatidic acid, 1-stearoyl-lysophosphatidic acid and 1-arachidonoyl-lysophosphatidic acid as lipid acceptor. Functions preferentially with arachidonoyl-CoA followed by oleoyl-CoA as acyl group donors (By similarity). Functions in phosphatidic acid biosynthesis . May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2 . Involved in keratinocyte differentiation . Regulates lipid droplet fusion (By similarity). . |
Accessions | A0A0S2Z572 ENST00000643500.1 A0A6B9MC78 A0A8E4IIP3 A0A0S2Z5D6 F6K7K5 ENST00000643477.1 ENST00000413300.2 ENST00000454293.2 Q8WTS1 A0A2R8Y7S6 ENST00000463153.2 F8W7B5 A0A2U3TZT9 A0A2R8YER6 A0A2R8YG27 ENST00000649763.1 C9J1D1 ENST00000456453.5 H7BZY9 F6K7K2 F6K7K3 ENST00000643140.1 A0A0M3LN66 ENST00000458276.7 ENST00000646378.1 ENST00000644371.2 F6K7K4 A0A2R8YG22 ENST00000013894.3 A0A2R8YEZ7 ENST00000646799.1 ENST00000642351.1 C9JBM3 |