SERPINB5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030198Biological processextracellular matrix organization
GO_0050678Biological processregulation of epithelial cell proliferation
GO_0002009Biological processmorphogenesis of an epithelium
GO_0060512Biological processprostate gland morphogenesis
GO_0010951Biological processnegative regulation of endopeptidase activity
GO_0001533Cellular componentcornified envelope
GO_0005615Cellular componentextracellular space
GO_0016528Cellular componentsarcoplasm
GO_0005737Cellular componentcytoplasm
GO_0004867Molecular functionserine-type endopeptidase inhibitor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSERPINB5
Protein nameSerpin B5 (Maspin) (Peptidase inhibitor 5) (PI-5)
Serpin family B member 5
SynonymsPI5
DescriptionFUNCTION: Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

AccessionsP36952
ENST00000489441.5 [P36952-2]
ENST00000424602.1
C9JLM5
ENST00000382771.9 [P36952-1]