FGFBP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0090050Biological processpositive regulation of cell migration involved in sprouting angiogenesis
GO_0007165Biological processsignal transduction
GO_0008285Biological processnegative regulation of cell population proliferation
GO_0045743Biological processpositive regulation of fibroblast growth factor receptor signaling pathway
GO_0051450Biological processmyoblast proliferation
GO_1903589Biological processpositive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
GO_2000288Biological processpositive regulation of myoblast proliferation
GO_0007267Biological processcell-cell signaling
GO_0008543Biological processfibroblast growth factor receptor signaling pathway
GO_0005615Cellular componentextracellular space
GO_0009986Cellular componentcell surface
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0008201Molecular functionheparin binding
GO_0017134Molecular functionfibroblast growth factor binding
GO_0005515Molecular functionprotein binding
GO_0019838Molecular functiongrowth factor binding

IV. Literature review

[source]
Gene nameFGFBP1
Protein nameFibroblast growth factor-binding protein 1 (FGF-BP) (FGF-BP1) (FGF-binding protein 1) (FGFBP-1) (17 kDa heparin-binding growth factor-binding protein) (17 kDa HBGF-binding protein) (HBp17)
SynonymsFGFBP
HBP17
DescriptionFUNCTION: Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth. .

AccessionsQ14512
ENST00000382333.2