Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 7 studies | 38% ± 15% | |
| basal cell | 5 studies | 27% ± 9% | |
| ciliated cell | 5 studies | 27% ± 16% | |
| squamous epithelial cell | 4 studies | 43% ± 24% | |
| keratinocyte | 4 studies | 27% ± 7% | |
| secretory cell | 3 studies | 33% ± 15% |
Insufficient scRNA-seq data for expression of DENND2C at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 87% | 551.31 | 197 / 226 | 84% | 2.79 | 342 / 406 |
| prostate | 79% | 499.85 | 194 / 245 | 81% | 1.67 | 405 / 502 |
| uterus | 65% | 388.29 | 111 / 170 | 81% | 8.54 | 372 / 459 |
| lung | 71% | 396.52 | 411 / 578 | 73% | 4.59 | 847 / 1155 |
| bladder | 71% | 547.57 | 15 / 21 | 65% | 3.26 | 330 / 504 |
| esophagus | 51% | 2102.80 | 733 / 1445 | 85% | 11.97 | 155 / 183 |
| thymus | 45% | 202.80 | 297 / 653 | 79% | 1.57 | 475 / 605 |
| skin | 77% | 3206.21 | 1392 / 1809 | 33% | 0.88 | 156 / 472 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 11.31 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1.60 | 1 / 1 |
| muscle | 99% | 3585.34 | 798 / 803 | 0% | 0 | 0 / 0 |
| breast | 46% | 218.53 | 211 / 459 | 52% | 1.07 | 586 / 1118 |
| pancreas | 12% | 56.22 | 39 / 328 | 74% | 1.54 | 131 / 178 |
| ovary | 50% | 212.88 | 90 / 180 | 30% | 0.47 | 127 / 430 |
| kidney | 2% | 9.34 | 2 / 89 | 52% | 1.14 | 471 / 901 |
| stomach | 14% | 67.59 | 52 / 359 | 37% | 0.74 | 106 / 286 |
| intestine | 21% | 90.96 | 199 / 966 | 25% | 0.86 | 131 / 527 |
| adipose | 39% | 183.73 | 467 / 1204 | 0% | 0 | 0 / 0 |
| brain | 5% | 21.97 | 124 / 2642 | 32% | 0.46 | 226 / 705 |
| blood vessel | 34% | 164.85 | 456 / 1335 | 0% | 0 | 0 / 0 |
| adrenal gland | 7% | 25.86 | 17 / 258 | 21% | 0.31 | 48 / 230 |
| heart | 23% | 105.48 | 194 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 14% | 0.20 | 11 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.04 | 1 / 29 |
| spleen | 2% | 7.10 | 4 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 1% | 5.24 | 12 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
| Gene name | DENND2C |
| Protein name | DENN domain-containing protein 2C |
| Synonyms | |
| Description | FUNCTION: Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. . |
| Accessions | ENST00000393274.6 [Q68D51-1] ENST00000393276.7 [Q68D51-3] Q68D51 |
