Insufficient scRNA-seq data for expression of CNR2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 92% | 72.89 | 599 / 653 | 20% | 0.48 | 118 / 605 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 31.34 | 29 / 29 |
| spleen | 100% | 2314.49 | 241 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 99% | 592.44 | 918 / 929 | 0% | 0 | 0 / 0 |
| lung | 71% | 22.42 | 408 / 578 | 17% | 0.47 | 194 / 1155 |
| liver | 51% | 11.62 | 115 / 226 | 2% | 0.19 | 10 / 406 |
| intestine | 45% | 213.73 | 437 / 966 | 6% | 0.41 | 34 / 527 |
| stomach | 25% | 10.31 | 90 / 359 | 12% | 0.32 | 33 / 286 |
| kidney | 35% | 20.35 | 31 / 89 | 2% | 0.06 | 14 / 901 |
| tonsil | 0% | 0 | 0 / 0 | 31% | 0.82 | 14 / 45 |
| prostate | 27% | 11.38 | 65 / 245 | 4% | 0.07 | 19 / 502 |
| bladder | 24% | 14.43 | 5 / 21 | 5% | 0.37 | 25 / 504 |
| esophagus | 19% | 8.55 | 270 / 1445 | 10% | 0.27 | 18 / 183 |
| breast | 11% | 2.71 | 52 / 459 | 9% | 0.31 | 103 / 1118 |
| adipose | 20% | 7.26 | 237 / 1204 | 0% | 0 | 0 / 0 |
| pancreas | 2% | 0.23 | 5 / 328 | 18% | 0.96 | 32 / 178 |
| skin | 2% | 0.37 | 34 / 1809 | 14% | 0.81 | 65 / 472 |
| blood vessel | 8% | 6.61 | 112 / 1335 | 0% | 0 | 0 / 0 |
| uterus | 4% | 0.52 | 7 / 170 | 3% | 0.06 | 12 / 459 |
| heart | 4% | 1.17 | 34 / 861 | 0% | 0 | 0 / 0 |
| adrenal gland | 3% | 0.57 | 8 / 258 | 0% | 0 | 0 / 230 |
| ovary | 2% | 0.62 | 4 / 180 | 1% | 0.01 | 3 / 430 |
| brain | 1% | 0.13 | 17 / 2642 | 1% | 0.13 | 4 / 705 |
| muscle | 1% | 0.12 | 6 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006954 | Biological process | inflammatory response |
| GO_0038171 | Biological process | cannabinoid signaling pathway |
| GO_0030595 | Biological process | leukocyte chemotaxis |
| GO_0032229 | Biological process | negative regulation of synaptic transmission, GABAergic |
| GO_0006955 | Biological process | immune response |
| GO_0045759 | Biological process | negative regulation of action potential |
| GO_0007189 | Biological process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
| GO_0007187 | Biological process | G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger |
| GO_0001975 | Biological process | response to amphetamine |
| GO_0033004 | Biological process | negative regulation of mast cell activation |
| GO_0019222 | Biological process | regulation of metabolic process |
| GO_0032496 | Biological process | response to lipopolysaccharide |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0031234 | Cellular component | extrinsic component of cytoplasmic side of plasma membrane |
| GO_0043204 | Cellular component | perikaryon |
| GO_0030425 | Cellular component | dendrite |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005515 | Molecular function | protein binding |
| GO_0004949 | Molecular function | cannabinoid receptor activity |
| Gene name | CNR2 |
| Protein name | Cannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5) |
| Synonyms | CB2B CB2A |
| Description | FUNCTION: Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis. . |
| Accessions | P34972 ENST00000374472.5 |