CNR2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CNR2 at tissue level.

III. Associated gene sets

GO_0006954Biological processinflammatory response
GO_0038171Biological processcannabinoid signaling pathway
GO_0030595Biological processleukocyte chemotaxis
GO_0032229Biological processnegative regulation of synaptic transmission, GABAergic
GO_0006955Biological processimmune response
GO_0045759Biological processnegative regulation of action potential
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0007187Biological processG protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO_0001975Biological processresponse to amphetamine
GO_0033004Biological processnegative regulation of mast cell activation
GO_0019222Biological processregulation of metabolic process
GO_0032496Biological processresponse to lipopolysaccharide
GO_0005886Cellular componentplasma membrane
GO_0031234Cellular componentextrinsic component of cytoplasmic side of plasma membrane
GO_0043204Cellular componentperikaryon
GO_0030425Cellular componentdendrite
GO_0005783Cellular componentendoplasmic reticulum
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding
GO_0004949Molecular functioncannabinoid receptor activity

IV. Literature review

[source]
Gene nameCNR2
Protein nameCannabinoid receptor 2 (CB-2) (CB2) (hCB2) (CX5)
SynonymsCB2B
CB2A
DescriptionFUNCTION: Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis. .

AccessionsP34972
ENST00000374472.5