I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| non-classical monocyte | 3 studies | 27% ± 6% | |
| dendritic cell | 3 studies | 22% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| non-classical monocyte | 3 studies | 27% ± 6% | |
| dendritic cell | 3 studies | 22% ± 7% |
Insufficient scRNA-seq data for expression of DNASE1L1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 691.26 | 1443 / 1445 | 100% | 8.03 | 183 / 183 |
| lung | 100% | 1050.49 | 577 / 578 | 99% | 8.82 | 1146 / 1155 |
| kidney | 100% | 762.58 | 89 / 89 | 99% | 10.18 | 892 / 901 |
| breast | 100% | 855.88 | 459 / 459 | 99% | 8.44 | 1103 / 1118 |
| bladder | 100% | 633.24 | 21 / 21 | 99% | 8.98 | 497 / 504 |
| stomach | 100% | 621.12 | 359 / 359 | 99% | 8.97 | 282 / 286 |
| adrenal gland | 100% | 1089.44 | 258 / 258 | 98% | 10.11 | 226 / 230 |
| intestine | 100% | 690.58 | 965 / 966 | 98% | 10.01 | 518 / 527 |
| prostate | 100% | 718.37 | 245 / 245 | 98% | 8.94 | 492 / 502 |
| thymus | 100% | 1210.29 | 653 / 653 | 98% | 9.84 | 591 / 605 |
| skin | 99% | 602.58 | 1787 / 1809 | 99% | 10.88 | 465 / 472 |
| uterus | 100% | 750.66 | 170 / 170 | 96% | 8.18 | 440 / 459 |
| ovary | 98% | 652.44 | 176 / 180 | 97% | 7.01 | 417 / 430 |
| pancreas | 96% | 352.08 | 315 / 328 | 98% | 9.27 | 175 / 178 |
| brain | 95% | 434.37 | 2508 / 2642 | 97% | 4.64 | 685 / 705 |
| liver | 98% | 408.44 | 221 / 226 | 78% | 3.99 | 316 / 406 |
| adipose | 100% | 817.61 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 7.38 | 29 / 29 |
| muscle | 100% | 3359.23 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1329.64 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 3.44 | 1 / 1 |
| blood vessel | 100% | 898.67 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 99% | 1054.11 | 919 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 7.79 | 79 / 80 |
| heart | 99% | 1024.23 | 850 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 7.40 | 44 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006308 | Biological process | DNA catabolic process |
| GO_0006259 | Biological process | DNA metabolic process |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005576 | Cellular component | extracellular region |
| GO_0035580 | Cellular component | specific granule lumen |
| GO_0005634 | Cellular component | nucleus |
| GO_0003677 | Molecular function | DNA binding |
| GO_0004536 | Molecular function | DNA nuclease activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0004530 | Molecular function | deoxyribonuclease I activity |
| Gene name | DNASE1L1 |
| Protein name | Deoxyribonuclease 1 like 1 Deoxyribonuclease-1-like 1 (DNase X) (Deoxyribonuclease I-like 1) Deoxyribonuclease-1-like 1 (EC 3.1.21.-) (DNase X) (Deoxyribonuclease I-like 1) (DNase I-like 1) (Muscle-specific DNase I-like) (XIB) |
| Synonyms | DNAS1L1 DNL1L |
| Description | |
| Accessions | ENST00000309585.9 ENST00000369808.7 P49184 ENST00000424626.5 ENST00000369807.6 ENST00000369809.5 Q5HY40 ENST00000451865.5 ENST00000014935.7 ENST00000393638.5 A6QRJ0 A3KQT1 ENST00000432135.1 ENST00000447892.1 ENST00000412184.1 E7EUJ0 E7ESG1 |
