Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 12 studies | 31% ± 9% | |
glutamatergic neuron | 9 studies | 57% ± 15% | |
astrocyte | 8 studies | 23% ± 8% | |
GABAergic neuron | 7 studies | 50% ± 20% | |
oligodendrocyte precursor cell | 7 studies | 34% ± 19% | |
neuron | 5 studies | 50% ± 15% | |
amacrine cell | 5 studies | 40% ± 13% | |
retinal ganglion cell | 4 studies | 89% ± 16% | |
retina horizontal cell | 4 studies | 50% ± 6% | |
interneuron | 4 studies | 50% ± 20% | |
endothelial cell | 3 studies | 31% ± 21% | |
retinal bipolar neuron | 3 studies | 39% ± 9% | |
rod bipolar cell | 3 studies | 37% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 40170.66 | 2640 / 2642 | 100% | 208.33 | 703 / 705 |
prostate | 33% | 1647.88 | 81 / 245 | 70% | 6.59 | 352 / 502 |
adrenal gland | 11% | 761.73 | 28 / 258 | 70% | 326.79 | 162 / 230 |
intestine | 3% | 118.64 | 31 / 966 | 49% | 6.40 | 256 / 527 |
stomach | 1% | 29.29 | 3 / 359 | 36% | 4.46 | 103 / 286 |
pancreas | 0% | 0 | 0 / 328 | 35% | 4.00 | 63 / 178 |
breast | 0% | 0 | 0 / 459 | 27% | 5.75 | 298 / 1118 |
bladder | 10% | 376.76 | 2 / 21 | 16% | 1.90 | 81 / 504 |
ovary | 1% | 64.72 | 2 / 180 | 23% | 3.66 | 98 / 430 |
uterus | 6% | 235.46 | 10 / 170 | 18% | 2.75 | 81 / 459 |
heart | 23% | 1154.06 | 194 / 861 | 0% | 0 | 0 / 0 |
esophagus | 2% | 63.26 | 22 / 1445 | 10% | 1.10 | 18 / 183 |
lung | 0% | 13.06 | 1 / 578 | 10% | 1.37 | 113 / 1155 |
thymus | 0% | 23.78 | 1 / 653 | 9% | 2.52 | 55 / 605 |
eye | 0% | 0 | 0 / 0 | 8% | 3.54 | 6 / 80 |
lymph node | 0% | 0 | 0 / 0 | 7% | 0.39 | 2 / 29 |
skin | 0% | 2.16 | 1 / 1809 | 3% | 0.42 | 16 / 472 |
blood vessel | 2% | 67.87 | 24 / 1335 | 0% | 0 | 0 / 0 |
kidney | 0% | 0 | 0 / 89 | 1% | 0.10 | 10 / 901 |
liver | 0% | 0 | 0 / 226 | 0% | 0.03 | 2 / 406 |
adipose | 0% | 12.95 | 3 / 1204 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0021549 | Biological process | cerebellum development |
GO_1902042 | Biological process | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors |
GO_0051402 | Biological process | neuron apoptotic process |
GO_0097190 | Biological process | apoptotic signaling pathway |
GO_0021681 | Biological process | cerebellar granular layer development |
GO_0043066 | Biological process | negative regulation of apoptotic process |
GO_0002931 | Biological process | response to ischemia |
GO_0021702 | Biological process | cerebellar Purkinje cell differentiation |
GO_0043524 | Biological process | negative regulation of neuron apoptotic process |
GO_2001234 | Biological process | negative regulation of apoptotic signaling pathway |
GO_0043523 | Biological process | regulation of neuron apoptotic process |
GO_0021680 | Biological process | cerebellar Purkinje cell layer development |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0045121 | Cellular component | membrane raft |
GO_0016020 | Cellular component | membrane |
GO_0045211 | Cellular component | postsynaptic membrane |
GO_0005515 | Molecular function | protein binding |
Gene name | FAIM2 |
Protein name | Protein lifeguard 2 (Fas apoptotic inhibitory molecule 2) (Neural membrane protein 35) (Transmembrane BAX inhibitor motif-containing protein 2) Protein lifeguard 2 (Fas apoptotic inhibitory molecule 2) |
Synonyms | KIAA0950 LFG2 TMBIM2 NMP35 LFG |
Description | FUNCTION: Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development. . |
Accessions | F8VV65 ENST00000547871.1 ENST00000552863.5 A0A0A0MTP9 ENST00000552669.5 ENST00000320634.8 [Q9BWQ8-1] F8VZI9 ENST00000550195.5 Q9BWQ8 F8W1L3 ENST00000550890.5 [Q9BWQ8-2] ENST00000550635.6 H0YIR3 |