Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| fibroblast | 13 studies | 24% ± 11% | |
| ciliated cell | 11 studies | 25% ± 8% | |
| type I pneumocyte | 5 studies | 24% ± 9% | |
| connective tissue cell | 4 studies | 31% ± 14% | |
| epithelial cell | 4 studies | 35% ± 10% | |
| precursor B cell | 4 studies | 33% ± 9% | |
| adventitial cell | 4 studies | 22% ± 6% | |
| glutamatergic neuron | 4 studies | 35% ± 15% | |
| astrocyte | 4 studies | 28% ± 8% | |
| pancreatic A cell | 3 studies | 35% ± 9% | |
| endothelial cell | 3 studies | 24% ± 6% | |
| pro-B cell | 3 studies | 39% ± 12% | |
| GABAergic neuron | 3 studies | 26% ± 9% | |
| basal cell | 3 studies | 20% ± 4% | |
| interneuron | 3 studies | 43% ± 14% | |
| epithelial cell of proximal tubule | 3 studies | 20% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1808.26 | 1445 / 1445 | 99% | 18.38 | 182 / 183 |
| lung | 100% | 2929.90 | 577 / 578 | 99% | 24.66 | 1148 / 1155 |
| pancreas | 100% | 4069.47 | 328 / 328 | 99% | 23.52 | 176 / 178 |
| intestine | 100% | 2223.81 | 965 / 966 | 99% | 20.71 | 521 / 527 |
| uterus | 100% | 3031.69 | 170 / 170 | 98% | 23.77 | 450 / 459 |
| breast | 99% | 1313.92 | 455 / 459 | 99% | 20.70 | 1104 / 1118 |
| stomach | 100% | 1728.94 | 359 / 359 | 97% | 16.85 | 278 / 286 |
| kidney | 100% | 1734.26 | 89 / 89 | 96% | 27.57 | 865 / 901 |
| bladder | 100% | 2357.19 | 21 / 21 | 95% | 18.76 | 480 / 504 |
| skin | 100% | 3769.75 | 1806 / 1809 | 95% | 22.31 | 449 / 472 |
| thymus | 100% | 1527.36 | 650 / 653 | 94% | 26.27 | 567 / 605 |
| prostate | 99% | 1176.37 | 242 / 245 | 80% | 6.12 | 401 / 502 |
| adrenal gland | 83% | 717.15 | 215 / 258 | 95% | 23.38 | 219 / 230 |
| ovary | 79% | 888.69 | 142 / 180 | 94% | 11.61 | 404 / 430 |
| liver | 58% | 441.76 | 132 / 226 | 80% | 9.88 | 323 / 406 |
| brain | 62% | 438.70 | 1636 / 2642 | 42% | 3.86 | 297 / 705 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 26.16 | 45 / 45 |
| blood vessel | 100% | 2633.37 | 1332 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 98% | 1471.57 | 1181 / 1204 | 0% | 0 | 0 / 0 |
| heart | 98% | 2863.48 | 844 / 861 | 0% | 0 | 0 / 0 |
| spleen | 98% | 969.04 | 235 / 241 | 0% | 0 | 0 / 0 |
| muscle | 75% | 549.32 | 603 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 74% | 6.88 | 59 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 45% | 3.92 | 13 / 29 |
| peripheral blood | 18% | 198.83 | 165 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0018401 | Biological process | peptidyl-proline hydroxylation to 4-hydroxy-L-proline |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0005788 | Cellular component | endoplasmic reticulum lumen |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005506 | Molecular function | iron ion binding |
| GO_0031418 | Molecular function | L-ascorbic acid binding |
| GO_0004656 | Molecular function | procollagen-proline 4-dioxygenase activity |
| GO_0009055 | Molecular function | electron transfer activity |
| Gene name | P4HA2 |
| Protein name | Prolyl 4-hydroxylase subunit alpha-2 (4-PH alpha-2) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2) Prolyl 4-hydroxylase subunit alpha 2 procollagen-proline 4-dioxygenase (EC 1.14.11.2) |
| Synonyms | UNQ290/PRO330 |
| Description | FUNCTION: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. . FUNCTION: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. . |
| Accessions | ENST00000428369.6 E7ERI1 ENST00000395164.5 ENST00000379104.7 [O15460-1] ENST00000428841.1 ENST00000379086.5 [O15460-2] A8MXE0 ENST00000416053.5 Q05DA4 C9JIG4 ENST00000431054.5 ENST00000439698.5 ENST00000360568.8 [O15460-2] ENST00000401867.5 [O15460-1] C9JX45 C9JFJ1 E7EPI9 C9JN43 ENST00000418055.5 C9JCP0 ENST00000166534.8 [O15460-1] ENST00000453286.5 E7ENX0 ENST00000417528.5 ENST00000379100.7 [O15460-2] O15460 |