Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 21 studies | 29% ± 12% | |
ciliated cell | 19 studies | 45% ± 19% | |
astrocyte | 17 studies | 34% ± 13% | |
macrophage | 10 studies | 27% ± 11% | |
non-classical monocyte | 10 studies | 23% ± 8% | |
endothelial cell | 9 studies | 23% ± 5% | |
B cell | 9 studies | 21% ± 4% | |
classical monocyte | 9 studies | 26% ± 7% | |
epithelial cell | 8 studies | 28% ± 9% | |
type I pneumocyte | 7 studies | 36% ± 11% | |
plasma cell | 6 studies | 28% ± 9% | |
basal cell | 6 studies | 24% ± 6% | |
conventional dendritic cell | 6 studies | 24% ± 11% | |
epithelial cell of proximal tubule | 6 studies | 23% ± 8% | |
microglial cell | 6 studies | 28% ± 9% | |
oligodendrocyte precursor cell | 6 studies | 28% ± 11% | |
adventitial cell | 5 studies | 27% ± 8% | |
hepatocyte | 5 studies | 53% ± 25% | |
plasmacytoid dendritic cell | 5 studies | 21% ± 3% | |
memory B cell | 5 studies | 21% ± 4% | |
endothelial cell of lymphatic vessel | 4 studies | 18% ± 4% | |
endothelial cell of artery | 4 studies | 18% ± 3% | |
goblet cell | 4 studies | 18% ± 3% | |
plasmablast | 3 studies | 38% ± 17% | |
kidney loop of Henle epithelial cell | 3 studies | 31% ± 7% | |
myeloid cell | 3 studies | 29% ± 4% | |
Mueller cell | 3 studies | 37% ± 6% | |
abnormal cell | 3 studies | 26% ± 3% | |
ependymal cell | 3 studies | 32% ± 17% | |
enterocyte | 3 studies | 20% ± 3% | |
mononuclear phagocyte | 3 studies | 25% ± 6% | |
naive B cell | 3 studies | 19% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 99% | 20793.54 | 224 / 226 | 99% | 332.85 | 403 / 406 |
brain | 98% | 7622.74 | 2591 / 2642 | 100% | 270.17 | 705 / 705 |
adrenal gland | 100% | 15610.03 | 257 / 258 | 97% | 194.02 | 223 / 230 |
thymus | 100% | 25192.06 | 653 / 653 | 96% | 334.76 | 582 / 605 |
kidney | 98% | 6234.98 | 87 / 89 | 97% | 159.68 | 870 / 901 |
pancreas | 96% | 6676.96 | 315 / 328 | 89% | 92.10 | 158 / 178 |
breast | 100% | 12923.68 | 458 / 459 | 84% | 60.21 | 939 / 1118 |
prostate | 96% | 5729.05 | 235 / 245 | 88% | 67.94 | 440 / 502 |
ovary | 99% | 8196.83 | 178 / 180 | 70% | 39.62 | 300 / 430 |
lung | 99% | 10420.34 | 573 / 578 | 69% | 51.11 | 796 / 1155 |
bladder | 95% | 10077.43 | 20 / 21 | 69% | 86.92 | 349 / 504 |
stomach | 100% | 13060.55 | 359 / 359 | 55% | 30.97 | 157 / 286 |
intestine | 99% | 11890.10 | 961 / 966 | 55% | 32.08 | 290 / 527 |
uterus | 98% | 8324.09 | 167 / 170 | 56% | 55.54 | 256 / 459 |
esophagus | 96% | 7906.43 | 1391 / 1445 | 43% | 26.85 | 79 / 183 |
skin | 91% | 5111.40 | 1647 / 1809 | 31% | 20.00 | 147 / 472 |
ureter | 0% | 0 | 0 / 0 | 100% | 78.95 | 1 / 1 |
adipose | 100% | 15987.06 | 1203 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 7408.21 | 240 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 98% | 9085.94 | 1309 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 97% | 86.90 | 28 / 29 |
muscle | 86% | 3924.29 | 690 / 803 | 0% | 0 | 0 / 0 |
heart | 67% | 2866.39 | 579 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 62% | 32.82 | 28 / 45 |
peripheral blood | 36% | 1195.00 | 339 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 4% | 1.48 | 3 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0042476 | Biological process | odontogenesis |
GO_0032259 | Biological process | methylation |
GO_0180035 | Biological process | lncRNA processing |
GO_0001649 | Biological process | osteoblast differentiation |
GO_1904724 | Cellular component | tertiary granule lumen |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005829 | Cellular component | cytosol |
GO_0005576 | Cellular component | extracellular region |
GO_0005811 | Cellular component | lipid droplet |
GO_0016020 | Cellular component | membrane |
GO_0008173 | Molecular function | RNA methyltransferase activity |
GO_0005515 | Molecular function | protein binding |
GO_0018708 | Molecular function | thiol S-methyltransferase activity |
GO_0001734 | Molecular function | mRNA m(6)A methyltransferase activity |
GO_0008168 | Molecular function | methyltransferase activity |
Gene name | TMT1A |
Protein name | Thiol S-methyltransferase TMT1A (EC 2.1.1.9) (Methyltransferase-like protein 7A) (N6-adenosine-methyltransferase TMT1A) (EC 2.1.1.348) (Protein AAM-B) (Thiol methyltransferase 1A) Methyltransferase like 7A |
Synonyms | PRO0066 UNQ1902/PRO4348 METTL7A |
Description | FUNCTION: Thiol S-methyltransferase that catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to alkyl and phenolic thiol-containing acceptor substrates. Together with TMT1B accounts for most of S-thiol methylation activity in the endoplasmic reticulum of hepatocytes . Able to methylate the N6 position of adenosine residues in long non-coding RNAs (lncRNAs). May facilitate lncRNAs transfer into exosomes at the tumor-stroma interface . Promotes osteogenic and odontogenic differentiation by regulating the expression of genes involved in stem cell differentiation and survival . Targeted from the endoplasmic reticulum to lipid droplets, where it recruits cellular proteins to form functional organelles . .; FUNCTION: (Microbial infection) May be involved in the assembly and release stages of hepatitis C virus (HCV) life cycle and thus play a crucial role in HCV propagation. . |
Accessions | F8VQX6 ENST00000548553.1 ENST00000332160.5 ENST00000550502.1 H0YI09 ENST00000550097.1 Q9H8H3 ENST00000547104.1 |