MBOAT7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0021591Biological processventricular system development
GO_0090207Biological processregulation of triglyceride metabolic process
GO_0021819Biological processlayer formation in cerebral cortex
GO_0036151Biological processphosphatidylcholine acyl-chain remodeling
GO_0030258Biological processlipid modification
GO_0036149Biological processphosphatidylinositol acyl-chain remodeling
GO_0006661Biological processphosphatidylinositol biosynthetic process
GO_0044233Cellular componentmitochondria-associated endoplasmic reticulum membrane contact site
GO_0005783Cellular componentendoplasmic reticulum
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0047144Molecular function2-acylglycerol-3-phosphate O-acyltransferase activity
GO_0003841Molecular function1-acylglycerol-3-phosphate O-acyltransferase activity
GO_0008374Molecular functionO-acyltransferase activity
GO_0071617Molecular functionlysophospholipid acyltransferase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMBOAT7
Protein nameLysophospholipid acyltransferase 7 (Membrane bound O-acyltransferase domain containing 7)
Lysophospholipid acyltransferase 7 (Leukocyte receptor cluster member 4) (Membrane-bound O-acyltransferase domain-containing protein 7)
Lysophospholipid acyltransferase 7
Lysophospholipid acyltransferase 7 (LPLAT 7) (EC 2.3.1.-) (1-acylglycerophosphatidylinositol O-acyltransferase) (Bladder and breast carcinoma-overexpressed gene 1 protein) (Leukocyte receptor cluster member 4) (Lysophosphatidylinositol acyltransferase) (LPIAT) (Lyso-PI acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 7) (O-acyltransferase domain-containing protein 7) (h-mboa-7)
SynonymsLENG4
BB1
OACT7
DescriptionFUNCTION: Acyltransferase which catalyzes the transfer of an acyl group from an acyl-CoA to a lysophosphatidylinositol (1-acylglycerophosphatidylinositol or LPI) leading to the production of a phosphatidylinositol (1,2-diacyl-sn-glycero-3-phosphoinositol or PI) and participates in the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle . Prefers arachidonoyl-CoA as the acyl donor, thus contributing to the regulation of free levels arachidonic acid in cell . In liver, participates in the regulation of triglyceride metabolism through the phosphatidylinositol acyl-chain remodeling regulation . .

AccessionsENST00000620636.1 [Q96N66-2]
ENST00000618899.4 [Q96N66-3]
ENST00000391754.5 [Q96N66-3]
ENST00000611602.4 [Q96N66-2]
ENST00000621875.4 [Q96N66-1]
C9J4E9
H7C2M4
ENST00000620231.4
ENST00000621455.4 [Q96N66-2]
ENST00000611239.1 [Q96N66-2]
ENST00000615453.4 [Q96N66-1]
ENST00000414665.5
ENST00000453320.1
ENST00000617012.4 [Q96N66-1]
ENST00000618826.4 [Q96N66-2]
ENST00000431666.6 [Q96N66-2]
A0A0G2JNX6
ENST00000621146.4 [Q96N66-2]
ENST00000615282.4 [Q96N66-2]
ENST00000620371.1 [Q96N66-2]
ENST00000437868.5
ENST00000621334.4
ENST00000449249.5
ENST00000619844.4
ENST00000619670.4 [Q96N66-3]
ENST00000338624.10 [Q96N66-2]
ENST00000618378.4 [Q96N66-1]
M0R1Z5
ENST00000610862.4 [Q96N66-3]
ENST00000617656.4 [Q96N66-2]
ENST00000620311.1 [Q96N66-2]
ENST00000619745.4 [Q96N66-2]
F8WD95
ENST00000614279.1 [Q96N66-2]
ENST00000613746.4 [Q96N66-1]
ENST00000245615.6 [Q96N66-1]
ENST00000617324.4
A9C4B8
ENST00000621612.4 [Q96N66-1]
ENST00000616849.4
ENST00000619842.4 [Q96N66-1]
ENST00000612519.1
ENST00000617772.1 [Q96N66-2]
ENST00000612053.1 [Q96N66-2]
ENST00000615872.4
ENST00000612567.1 [Q96N66-2]
ENST00000612092.1
ENST00000495279.2
ENST00000617095.4
Q96N66
ENST00000613506.4 [Q96N66-1]
ENST00000619855.4 [Q96N66-1]