Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| mast cell | 16 studies | 29% ± 11% | |
| classical monocyte | 12 studies | 33% ± 16% | |
| neutrophil | 9 studies | 27% ± 7% | |
| monocyte | 8 studies | 20% ± 3% | |
| conventional dendritic cell | 7 studies | 36% ± 22% | |
| hematopoietic precursor cell | 6 studies | 40% ± 21% | |
| endothelial cell | 5 studies | 23% ± 5% | |
| macrophage | 5 studies | 23% ± 11% | |
| epithelial cell | 5 studies | 36% ± 14% | |
| non-classical monocyte | 4 studies | 30% ± 11% | |
| myeloid cell | 4 studies | 32% ± 12% | |
| abnormal cell | 4 studies | 18% ± 2% | |
| dendritic cell | 4 studies | 30% ± 19% | |
| hematopoietic stem cell | 4 studies | 42% ± 21% | |
| neuron | 3 studies | 22% ± 3% | |
| glutamatergic neuron | 3 studies | 18% ± 2% | |
| ciliated cell | 3 studies | 30% ± 5% | |
| enteroendocrine cell | 3 studies | 21% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 100% | 3941.56 | 180 / 180 | 100% | 83.67 | 430 / 430 |
| esophagus | 100% | 3303.46 | 1444 / 1445 | 100% | 76.71 | 183 / 183 |
| intestine | 100% | 4200.35 | 966 / 966 | 100% | 67.20 | 526 / 527 |
| adrenal gland | 100% | 19986.22 | 258 / 258 | 100% | 106.56 | 229 / 230 |
| uterus | 100% | 3372.84 | 170 / 170 | 100% | 82.47 | 457 / 459 |
| skin | 100% | 3922.09 | 1807 / 1809 | 100% | 59.39 | 470 / 472 |
| bladder | 100% | 5239.14 | 21 / 21 | 99% | 121.42 | 501 / 504 |
| prostate | 100% | 4681.62 | 245 / 245 | 99% | 57.65 | 499 / 502 |
| pancreas | 99% | 2352.00 | 326 / 328 | 100% | 66.25 | 178 / 178 |
| brain | 100% | 5856.06 | 2629 / 2642 | 100% | 50.53 | 704 / 705 |
| stomach | 100% | 2909.26 | 359 / 359 | 99% | 68.44 | 284 / 286 |
| thymus | 100% | 3475.02 | 651 / 653 | 99% | 61.74 | 601 / 605 |
| lung | 99% | 4523.44 | 575 / 578 | 99% | 62.82 | 1147 / 1155 |
| kidney | 100% | 4032.90 | 89 / 89 | 99% | 46.57 | 888 / 901 |
| breast | 99% | 2563.36 | 456 / 459 | 99% | 91.14 | 1107 / 1118 |
| liver | 98% | 2086.08 | 222 / 226 | 95% | 31.34 | 385 / 406 |
| eye | 0% | 0 | 0 / 0 | 100% | 51.41 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 27.87 | 29 / 29 |
| peripheral blood | 100% | 28765.79 | 929 / 929 | 0% | 0 | 0 / 0 |
| spleen | 100% | 6088.37 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 49.87 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 90.06 | 1 / 1 |
| blood vessel | 99% | 2334.43 | 1320 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 99% | 2330.98 | 1190 / 1204 | 0% | 0 | 0 / 0 |
| heart | 79% | 1354.86 | 678 / 861 | 0% | 0 | 0 / 0 |
| muscle | 19% | 222.75 | 150 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0021591 | Biological process | ventricular system development |
| GO_0090207 | Biological process | regulation of triglyceride metabolic process |
| GO_0021819 | Biological process | layer formation in cerebral cortex |
| GO_0036151 | Biological process | phosphatidylcholine acyl-chain remodeling |
| GO_0030258 | Biological process | lipid modification |
| GO_0036149 | Biological process | phosphatidylinositol acyl-chain remodeling |
| GO_0006661 | Biological process | phosphatidylinositol biosynthetic process |
| GO_0044233 | Cellular component | mitochondria-associated endoplasmic reticulum membrane contact site |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0016020 | Cellular component | membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0047144 | Molecular function | 2-acylglycerol-3-phosphate O-acyltransferase activity |
| GO_0003841 | Molecular function | 1-acylglycerol-3-phosphate O-acyltransferase activity |
| GO_0008374 | Molecular function | O-acyltransferase activity |
| GO_0071617 | Molecular function | lysophospholipid acyltransferase activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | MBOAT7 |
| Protein name | Lysophospholipid acyltransferase 7 (Membrane bound O-acyltransferase domain containing 7) Lysophospholipid acyltransferase 7 (Leukocyte receptor cluster member 4) (Membrane-bound O-acyltransferase domain-containing protein 7) Lysophospholipid acyltransferase 7 Lysophospholipid acyltransferase 7 (LPLAT 7) (EC 2.3.1.-) (1-acylglycerophosphatidylinositol O-acyltransferase) (Bladder and breast carcinoma-overexpressed gene 1 protein) (Leukocyte receptor cluster member 4) (Lysophosphatidylinositol acyltransferase) (LPIAT) (Lyso-PI acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 7) (O-acyltransferase domain-containing protein 7) (h-mboa-7) |
| Synonyms | LENG4 BB1 OACT7 |
| Description | FUNCTION: Acyltransferase which catalyzes the transfer of an acyl group from an acyl-CoA to a lysophosphatidylinositol (1-acylglycerophosphatidylinositol or LPI) leading to the production of a phosphatidylinositol (1,2-diacyl-sn-glycero-3-phosphoinositol or PI) and participates in the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle . Prefers arachidonoyl-CoA as the acyl donor, thus contributing to the regulation of free levels arachidonic acid in cell . In liver, participates in the regulation of triglyceride metabolism through the phosphatidylinositol acyl-chain remodeling regulation . . |
| Accessions | ENST00000620636.1 [Q96N66-2] ENST00000618899.4 [Q96N66-3] ENST00000391754.5 [Q96N66-3] ENST00000611602.4 [Q96N66-2] ENST00000621875.4 [Q96N66-1] C9J4E9 H7C2M4 ENST00000620231.4 ENST00000621455.4 [Q96N66-2] ENST00000611239.1 [Q96N66-2] ENST00000615453.4 [Q96N66-1] ENST00000414665.5 ENST00000453320.1 ENST00000617012.4 [Q96N66-1] ENST00000618826.4 [Q96N66-2] ENST00000431666.6 [Q96N66-2] A0A0G2JNX6 ENST00000621146.4 [Q96N66-2] ENST00000615282.4 [Q96N66-2] ENST00000620371.1 [Q96N66-2] ENST00000437868.5 ENST00000621334.4 ENST00000449249.5 ENST00000619844.4 ENST00000619670.4 [Q96N66-3] ENST00000338624.10 [Q96N66-2] ENST00000618378.4 [Q96N66-1] M0R1Z5 ENST00000610862.4 [Q96N66-3] ENST00000617656.4 [Q96N66-2] ENST00000620311.1 [Q96N66-2] ENST00000619745.4 [Q96N66-2] F8WD95 ENST00000614279.1 [Q96N66-2] ENST00000613746.4 [Q96N66-1] ENST00000245615.6 [Q96N66-1] ENST00000617324.4 A9C4B8 ENST00000621612.4 [Q96N66-1] ENST00000616849.4 ENST00000619842.4 [Q96N66-1] ENST00000612519.1 ENST00000617772.1 [Q96N66-2] ENST00000612053.1 [Q96N66-2] ENST00000615872.4 ENST00000612567.1 [Q96N66-2] ENST00000612092.1 ENST00000495279.2 ENST00000617095.4 Q96N66 ENST00000613506.4 [Q96N66-1] ENST00000619855.4 [Q96N66-1] |