Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 23 studies | 39% ± 16% | |
oligodendrocyte | 14 studies | 48% ± 13% | |
glutamatergic neuron | 11 studies | 41% ± 20% | |
adipocyte | 8 studies | 28% ± 7% | |
GABAergic neuron | 7 studies | 53% ± 23% | |
retinal cone cell | 6 studies | 56% ± 29% | |
neuron | 4 studies | 30% ± 13% | |
retinal rod cell | 4 studies | 65% ± 12% | |
interneuron | 4 studies | 48% ± 20% | |
pericyte | 3 studies | 20% ± 4% | |
capillary endothelial cell | 3 studies | 29% ± 13% | |
endothelial cell of artery | 3 studies | 31% ± 3% | |
vein endothelial cell | 3 studies | 40% ± 21% | |
endothelial cell of vascular tree | 3 studies | 56% ± 25% | |
retinal pigment epithelial cell | 3 studies | 44% ± 21% | |
microglial cell | 3 studies | 41% ± 17% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 2475.92 | 459 / 459 | 93% | 4.24 | 1035 / 1118 |
thymus | 100% | 1600.07 | 653 / 653 | 87% | 2.96 | 529 / 605 |
brain | 89% | 2771.09 | 2339 / 2642 | 97% | 6.28 | 686 / 705 |
prostate | 98% | 1303.44 | 240 / 245 | 83% | 2.01 | 418 / 502 |
lung | 93% | 992.90 | 540 / 578 | 80% | 2.51 | 929 / 1155 |
kidney | 100% | 1283.66 | 89 / 89 | 73% | 5.93 | 655 / 901 |
intestine | 88% | 796.61 | 847 / 966 | 82% | 2.67 | 432 / 527 |
stomach | 70% | 456.75 | 251 / 359 | 83% | 2.50 | 238 / 286 |
ovary | 99% | 4051.08 | 179 / 180 | 53% | 1.28 | 227 / 430 |
esophagus | 74% | 557.39 | 1068 / 1445 | 78% | 2.27 | 142 / 183 |
bladder | 90% | 752.14 | 19 / 21 | 60% | 1.68 | 304 / 504 |
uterus | 98% | 1056.55 | 167 / 170 | 41% | 1.05 | 190 / 459 |
skin | 40% | 220.26 | 719 / 1809 | 66% | 1.43 | 313 / 472 |
pancreas | 12% | 50.49 | 39 / 328 | 93% | 4.47 | 165 / 178 |
adipose | 100% | 2703.61 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 95% | 637.04 | 230 / 241 | 0% | 0 | 0 / 0 |
adrenal gland | 29% | 159.10 | 74 / 258 | 66% | 1.98 | 151 / 230 |
heart | 94% | 741.44 | 812 / 861 | 0% | 0 | 0 / 0 |
muscle | 79% | 433.54 | 634 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 76% | 600.76 | 1019 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 69% | 1.89 | 20 / 29 |
liver | 1% | 4.55 | 2 / 226 | 59% | 1.67 | 240 / 406 |
tonsil | 0% | 0 | 0 / 0 | 53% | 1.02 | 24 / 45 |
eye | 0% | 0 | 0 / 0 | 35% | 0.70 | 28 / 80 |
peripheral blood | 19% | 103.49 | 172 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0051056 | Biological process | regulation of small GTPase mediated signal transduction |
GO_0007265 | Biological process | Ras protein signal transduction |
GO_0060291 | Biological process | long-term synaptic potentiation |
GO_0034976 | Biological process | response to endoplasmic reticulum stress |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005829 | Cellular component | cytosol |
GO_0005886 | Cellular component | plasma membrane |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0005516 | Molecular function | calmodulin binding |
Gene name | RASGRF2 |
Protein name | Ras protein specific guanine nucleotide releasing factor 2 RASGRF2 Ras-specific guanine nucleotide-releasing factor 2 (Ras-GRF2) (Ras guanine nucleotide exchange factor 2) |
Synonyms | GRF2 |
Description | FUNCTION: Functions as a calcium-regulated nucleotide exchange factor activating both Ras and RAC1 through the exchange of bound GDP for GTP. Preferentially activates HRAS in vivo compared to RRAS based on their different types of prenylation. Functions in synaptic plasticity by contributing to the induction of long term potentiation. . |
Accessions | ENST00000265080.9 ENST00000638442.1 D6RAS9 O14827 A0A2X0SFL3 A0A1W2PP99 ENST00000503795.1 |