Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 5 studies | 23% ± 5% | |
glutamatergic neuron | 5 studies | 44% ± 22% | |
oligodendrocyte | 5 studies | 21% ± 4% | |
epithelial cell | 4 studies | 41% ± 12% | |
ciliated cell | 4 studies | 25% ± 3% | |
basal cell | 4 studies | 34% ± 21% | |
oligodendrocyte precursor cell | 4 studies | 22% ± 4% | |
ionocyte | 3 studies | 34% ± 3% | |
fibroblast | 3 studies | 18% ± 2% | |
GABAergic neuron | 3 studies | 50% ± 4% | |
astrocyte | 3 studies | 29% ± 7% | |
interneuron | 3 studies | 42% ± 23% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 5 studies | 38% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1665.98 | 1445 / 1445 | 100% | 37.54 | 183 / 183 |
breast | 100% | 1207.36 | 459 / 459 | 99% | 22.83 | 1111 / 1118 |
prostate | 100% | 1426.23 | 245 / 245 | 99% | 15.48 | 498 / 502 |
lung | 100% | 1230.06 | 577 / 578 | 99% | 25.96 | 1145 / 1155 |
uterus | 100% | 1432.61 | 170 / 170 | 98% | 20.78 | 451 / 459 |
kidney | 100% | 899.75 | 89 / 89 | 98% | 19.98 | 879 / 901 |
thymus | 100% | 1200.60 | 651 / 653 | 96% | 11.08 | 582 / 605 |
brain | 99% | 926.32 | 2610 / 2642 | 97% | 9.50 | 684 / 705 |
bladder | 100% | 1599.76 | 21 / 21 | 95% | 17.05 | 481 / 504 |
adrenal gland | 100% | 910.40 | 257 / 258 | 96% | 11.03 | 220 / 230 |
ovary | 100% | 1160.30 | 180 / 180 | 94% | 9.22 | 403 / 430 |
stomach | 100% | 881.16 | 358 / 359 | 93% | 11.88 | 266 / 286 |
pancreas | 93% | 453.05 | 306 / 328 | 97% | 11.16 | 172 / 178 |
intestine | 100% | 1248.30 | 966 / 966 | 89% | 9.54 | 471 / 527 |
skin | 100% | 2983.20 | 1809 / 1809 | 83% | 9.41 | 391 / 472 |
liver | 100% | 771.19 | 225 / 226 | 67% | 5.04 | 273 / 406 |
tonsil | 0% | 0 | 0 / 0 | 100% | 31.82 | 45 / 45 |
adipose | 100% | 1171.99 | 1203 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1336.16 | 1333 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 718.99 | 240 / 241 | 0% | 0 | 0 / 0 |
heart | 96% | 596.49 | 826 / 861 | 0% | 0 | 0 / 0 |
muscle | 81% | 329.53 | 652 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 34% | 1.89 | 10 / 29 |
peripheral blood | 22% | 130.91 | 209 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 16% | 0.81 | 13 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_1901800 | Biological process | positive regulation of proteasomal protein catabolic process |
GO_0035269 | Biological process | protein O-linked mannosylation |
GO_0034976 | Biological process | response to endoplasmic reticulum stress |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0016020 | Cellular component | membrane |
GO_0004169 | Molecular function | dolichyl-phosphate-mannose-protein mannosyltransferase activity |
GO_0005515 | Molecular function | protein binding |
GO_0000030 | Molecular function | mannosyltransferase activity |
Gene name | TMTC3 |
Protein name | Transmembrane O-mannosyltransferase targeting cadherins 3 Alternative protein TMTC3 Protein O-mannosyl-transferase TMTC3 (EC 2.4.1.109) (Protein SMILE) (Transmembrane O-mannosyltransferase targeting cadherins 3) (Transmembrane and tetratricopeptide repeat-containing 3) |
Synonyms | |
Description | FUNCTION: Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O-mannosyl-transferase on other proteins such as PDIA3 . Involved in the positive regulation of proteasomal protein degradation in the endoplasmic reticulum (ER), and the control of ER stress response. . |
Accessions | ENST00000266712.11 [Q6ZXV5-2] F8W044 ENST00000549011.5 ENST00000547034.5 Q6ZXV5 ENST00000551088.1 F8VRY4 F8VR71 L8ECP4 |