DEGS1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030148Biological processsphingolipid biosynthetic process
GO_0006636Biological processunsaturated fatty acid biosynthetic process
GO_0043217Biological processmyelin maintenance
GO_0046513Biological processceramide biosynthetic process
GO_0031966Cellular componentmitochondrial membrane
GO_0005783Cellular componentendoplasmic reticulum
GO_0035579Cellular componentspecific granule membrane
GO_0016020Cellular componentmembrane
GO_0005886Cellular componentplasma membrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005739Cellular componentmitochondrion
GO_0042284Molecular functionsphingolipid delta-4 desaturase activity
GO_0050251Molecular functionretinol isomerase activity
GO_0005515Molecular functionprotein binding
GO_0009055Molecular functionelectron transfer activity

IV. Literature review

[source]
Gene nameDEGS1
Protein nameSphingolipid delta(4)-desaturase DES1 (EC 1.14.19.17) (Cell migration-inducing gene 15 protein) (Degenerative spermatocyte homolog 1) (Dihydroceramide desaturase-1) (Membrane lipid desaturase) (Retinol isomerase) (EC 5.2.1.-)
Sphingolipid delta(4)-desaturase DES1 (Degenerative spermatocyte homolog 1) (Dihydroceramide desaturase-1) (Retinol isomerase)
SynonymsMIG15
DES1
MLD
DescriptionFUNCTION: Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine) . Catalyzes the equilibrium isomerization of retinols (By similarity). .

AccessionsENST00000415210.5
E7EMA0
ENST00000323699.9
O15121