Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 4363.75 | 245 / 245 | 100% | 327.68 | 502 / 502 |
skin | 100% | 27741.67 | 1809 / 1809 | 100% | 152.42 | 471 / 472 |
thymus | 100% | 4040.30 | 652 / 653 | 100% | 183.66 | 603 / 605 |
breast | 100% | 4572.12 | 459 / 459 | 99% | 182.44 | 1112 / 1118 |
lung | 100% | 4511.56 | 576 / 578 | 99% | 107.77 | 1148 / 1155 |
uterus | 100% | 3803.19 | 170 / 170 | 98% | 105.48 | 451 / 459 |
ovary | 99% | 2548.56 | 178 / 180 | 99% | 102.01 | 427 / 430 |
brain | 98% | 2652.07 | 2576 / 2642 | 100% | 136.22 | 705 / 705 |
esophagus | 100% | 4762.78 | 1440 / 1445 | 98% | 92.74 | 179 / 183 |
adrenal gland | 99% | 2558.02 | 255 / 258 | 95% | 104.50 | 219 / 230 |
stomach | 100% | 3058.19 | 358 / 359 | 93% | 64.01 | 267 / 286 |
kidney | 93% | 2435.92 | 83 / 89 | 96% | 154.68 | 869 / 901 |
intestine | 97% | 3647.51 | 936 / 966 | 90% | 52.81 | 476 / 527 |
bladder | 100% | 4056.90 | 21 / 21 | 84% | 70.49 | 421 / 504 |
liver | 73% | 1285.00 | 166 / 226 | 84% | 50.87 | 343 / 406 |
pancreas | 60% | 808.96 | 196 / 328 | 97% | 76.21 | 172 / 178 |
adipose | 100% | 4994.57 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 3036.86 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 76.65 | 1 / 1 |
blood vessel | 100% | 5270.80 | 1333 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 89.86 | 44 / 45 |
lymph node | 0% | 0 | 0 / 0 | 97% | 80.45 | 28 / 29 |
eye | 0% | 0 | 0 / 0 | 95% | 66.75 | 76 / 80 |
heart | 95% | 2675.10 | 814 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 90% | 2567.40 | 833 / 929 | 0% | 0 | 0 / 0 |
muscle | 69% | 946.11 | 556 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0030148 | Biological process | sphingolipid biosynthetic process |
GO_0006636 | Biological process | unsaturated fatty acid biosynthetic process |
GO_0043217 | Biological process | myelin maintenance |
GO_0046513 | Biological process | ceramide biosynthetic process |
GO_0031966 | Cellular component | mitochondrial membrane |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0035579 | Cellular component | specific granule membrane |
GO_0016020 | Cellular component | membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0005739 | Cellular component | mitochondrion |
GO_0042284 | Molecular function | sphingolipid delta-4 desaturase activity |
GO_0050251 | Molecular function | retinol isomerase activity |
GO_0005515 | Molecular function | protein binding |
GO_0009055 | Molecular function | electron transfer activity |
Gene name | DEGS1 |
Protein name | Sphingolipid delta(4)-desaturase DES1 (EC 1.14.19.17) (Cell migration-inducing gene 15 protein) (Degenerative spermatocyte homolog 1) (Dihydroceramide desaturase-1) (Membrane lipid desaturase) (Retinol isomerase) (EC 5.2.1.-) Sphingolipid delta(4)-desaturase DES1 (Degenerative spermatocyte homolog 1) (Dihydroceramide desaturase-1) (Retinol isomerase) |
Synonyms | MIG15 DES1 MLD |
Description | FUNCTION: Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine) . Catalyzes the equilibrium isomerization of retinols (By similarity). . |
Accessions | ENST00000415210.5 E7EMA0 ENST00000323699.9 O15121 |