GPAT3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006654Biological processphosphatidic acid biosynthetic process
GO_0019432Biological processtriglyceride biosynthetic process
GO_0032006Biological processregulation of TOR signaling
GO_0006072Biological processglycerol-3-phosphate metabolic process
GO_0016024Biological processCDP-diacylglycerol biosynthetic process
GO_0005783Cellular componentendoplasmic reticulum
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0004366Molecular functionglycerol-3-phosphate O-acyltransferase activity
GO_0003841Molecular function1-acylglycerol-3-phosphate O-acyltransferase activity
GO_0102420Molecular functionsn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity

IV. Literature review

[source]
Gene nameGPAT3
Protein nameGlycerol-3-phosphate acyltransferase 3 (GPAT-3) (EC 2.3.1.15) (1-acyl-sn-glycerol-3-phosphate O-acyltransferase 10) (AGPAT 10) (1-acyl-sn-glycerol-3-phosphate O-acyltransferase 9) (1-AGP acyltransferase 9) (1-AGPAT 9) (EC 2.3.1.51) (Acyl-CoA:glycerol-3-phosphate acyltransferase 3) (hGPAT3) (Lung cancer metastasis-associated protein 1) (Lysophosphatidic acid acyltransferase theta) (LPAAT-theta) (MAG-1)
SynonymsMAG1
HMFN0839
AGPAT9
UNQ2753/PRO6492
DescriptionFUNCTION: Converts glycerol-3-phosphate to 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) by incorporating an acyl moiety at the sn-1 position of the glycerol backbone . Also converts LPA into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone . Protects cells against lipotoxicity . .

AccessionsENST00000611707.4
ENST00000395226.6
ENST00000264409.5
Q53EU6