UFSP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006508Biological processproteolysis
GO_0032790Biological processribosome disassembly
GO_0033146Biological processregulation of intracellular estrogen receptor signaling pathway
GO_0005783Cellular componentendoplasmic reticulum
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0071567Molecular functiondeUFMylase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameUFSP2
Protein nameUFM1 specific peptidase 2
Ufm1-specific protease 2 (UfSP2) (EC 3.4.22.-)
Ufm1-specific protease 2
SynonymsC4orf20
DescriptionFUNCTION: Thiol-dependent isopeptidase that recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins . Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins . Through TRIP4 deufmylation may regulate intracellular nuclear receptors transactivation and thereby regulate cell proliferation and differentiation . .

AccessionsD6RB53
Q9NUQ7
H0Y9B0
D6RA67
ENST00000264689.11
ENST00000514247.5
H0YA18
ENST00000505357.1
D6RGX2
ENST00000509180.1
ENST00000510755.5
ENST00000502428.5
D6R9J7
ENST00000511485.5