Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 19 studies | 52% ± 26% | |
ciliated cell | 17 studies | 66% ± 20% | |
goblet cell | 14 studies | 81% ± 12% | |
basal cell | 12 studies | 54% ± 21% | |
secretory cell | 11 studies | 69% ± 22% | |
type II pneumocyte | 9 studies | 45% ± 16% | |
club cell | 9 studies | 67% ± 27% | |
enterocyte | 8 studies | 49% ± 17% | |
respiratory goblet cell | 7 studies | 76% ± 22% | |
macrophage | 7 studies | 50% ± 20% | |
progenitor cell | 6 studies | 76% ± 25% | |
intestinal crypt stem cell | 5 studies | 67% ± 28% | |
transit amplifying cell | 5 studies | 72% ± 29% | |
deuterosomal cell | 4 studies | 67% ± 7% | |
duct epithelial cell | 4 studies | 72% ± 11% | |
enteroendocrine cell | 4 studies | 45% ± 25% | |
mucus secreting cell | 4 studies | 85% ± 13% | |
luminal hormone-sensing cell of mammary gland | 4 studies | 55% ± 8% | |
luminal cell of prostate epithelium | 4 studies | 34% ± 13% | |
ionocyte | 3 studies | 34% ± 5% | |
squamous epithelial cell | 3 studies | 55% ± 22% | |
neuroendocrine cell | 3 studies | 33% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 96% | 5671.28 | 234 / 245 | 86% | 641.99 | 433 / 502 |
stomach | 80% | 27576.60 | 288 / 359 | 92% | 1012.52 | 263 / 286 |
intestine | 60% | 11817.92 | 584 / 966 | 94% | 1227.22 | 496 / 527 |
pancreas | 71% | 869.24 | 232 / 328 | 84% | 782.89 | 149 / 178 |
lung | 79% | 2595.90 | 459 / 578 | 63% | 554.11 | 723 / 1155 |
breast | 54% | 1380.33 | 250 / 459 | 74% | 824.47 | 825 / 1118 |
bladder | 62% | 4275.76 | 13 / 21 | 61% | 427.48 | 305 / 504 |
esophagus | 15% | 379.08 | 210 / 1445 | 50% | 719.47 | 92 / 183 |
kidney | 47% | 837.75 | 42 / 89 | 2% | 6.06 | 14 / 901 |
uterus | 9% | 452.52 | 15 / 170 | 30% | 271.21 | 136 / 459 |
thymus | 15% | 76.93 | 96 / 653 | 19% | 40.55 | 115 / 605 |
tonsil | 0% | 0 | 0 / 0 | 11% | 29.14 | 5 / 45 |
skin | 9% | 43.77 | 166 / 1809 | 0% | 0 | 0 / 472 |
liver | 1% | 5.50 | 2 / 226 | 5% | 33.20 | 22 / 406 |
ovary | 1% | 5.96 | 2 / 180 | 3% | 6.14 | 13 / 430 |
adrenal gland | 1% | 22.63 | 2 / 258 | 0% | 0 | 0 / 230 |
heart | 0% | 2.86 | 4 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 0% | 8.54 | 6 / 1335 | 0% | 0 | 0 / 0 |
adipose | 0% | 4.00 | 5 / 1204 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 20.90 | 2 / 929 | 0% | 0 | 0 / 0 |
muscle | 0% | 4.59 | 1 / 803 | 0% | 0 | 0 / 0 |
brain | 0% | 0.36 | 2 / 2642 | 0% | 0 | 0 / 705 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006954 | Biological process | inflammatory response |
GO_0034976 | Biological process | response to endoplasmic reticulum stress |
GO_0010811 | Biological process | positive regulation of cell-substrate adhesion |
GO_1903896 | Biological process | positive regulation of IRE1-mediated unfolded protein response |
GO_0010628 | Biological process | positive regulation of gene expression |
GO_0048639 | Biological process | positive regulation of developmental growth |
GO_1903078 | Biological process | positive regulation of protein localization to plasma membrane |
GO_0045742 | Biological process | positive regulation of epidermal growth factor receptor signaling pathway |
GO_1903899 | Biological process | positive regulation of PERK-mediated unfolded protein response |
GO_0060480 | Biological process | lung goblet cell differentiation |
GO_0070254 | Biological process | mucus secretion |
GO_0048546 | Biological process | digestive tract morphogenesis |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005154 | Molecular function | epidermal growth factor receptor binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0002162 | Molecular function | dystroglycan binding |
GO_0005515 | Molecular function | protein binding |
Gene name | AGR2 |
Protein name | Anterior gradient 2, protein disulphide isomerase family member Anterior gradient protein 2 homolog (AG-2) (hAG-2) (HPC8) (Secreted cement gland protein XAG-2 homolog) AGR2 (Anterior gradient 2 homolog (Xenopus laevis)) (Anterior gradient 2 splice variant C) (Epididymis secretory protein Li 116) AGR2 |
Synonyms | HEL-S-116 AG2 tcag7.197 UNQ515/PRO1030 hCG_19292 |
Description | FUNCTION: Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. Promotes cell adhesion . . |
Accessions | ENST00000450569.5 H7C3Z9 Q4JM47 ENST00000419304.7 ENST00000412973.1 C9J3E2 ENST00000401412.5 Q4JM46 O95994 B5MC07 |