I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell of proximal tubule | 6 studies | 41% ± 19% | |
| hepatocyte | 5 studies | 77% ± 14% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell of proximal tubule | 6 studies | 41% ± 19% | |
| hepatocyte | 5 studies | 77% ± 14% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 34351.47 | 226 / 226 | 96% | 200.92 | 388 / 406 |
| kidney | 100% | 8758.33 | 89 / 89 | 74% | 28.68 | 664 / 901 |
| prostate | 94% | 369.58 | 231 / 245 | 49% | 1.01 | 245 / 502 |
| ovary | 96% | 311.22 | 172 / 180 | 46% | 1.15 | 199 / 430 |
| brain | 95% | 445.95 | 2499 / 2642 | 44% | 1.00 | 311 / 705 |
| adrenal gland | 88% | 141.76 | 227 / 258 | 33% | 3.62 | 75 / 230 |
| uterus | 75% | 113.55 | 127 / 170 | 19% | 0.84 | 89 / 459 |
| bladder | 76% | 110.48 | 16 / 21 | 10% | 0.56 | 52 / 504 |
| thymus | 67% | 89.38 | 440 / 653 | 11% | 0.42 | 68 / 605 |
| intestine | 58% | 85.40 | 565 / 966 | 6% | 0.63 | 34 / 527 |
| pancreas | 37% | 58.11 | 122 / 328 | 26% | 6.18 | 46 / 178 |
| blood vessel | 61% | 126.74 | 815 / 1335 | 0% | 0 | 0 / 0 |
| esophagus | 47% | 64.07 | 673 / 1445 | 9% | 0.53 | 17 / 183 |
| heart | 53% | 54.40 | 458 / 861 | 0% | 0 | 0 / 0 |
| breast | 27% | 28.18 | 122 / 459 | 11% | 0.41 | 127 / 1118 |
| stomach | 25% | 32.50 | 89 / 359 | 8% | 0.34 | 23 / 286 |
| lung | 9% | 7.41 | 50 / 578 | 17% | 0.81 | 199 / 1155 |
| skin | 11% | 10.55 | 199 / 1809 | 8% | 0.22 | 38 / 472 |
| adipose | 13% | 13.54 | 157 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 13% | 34.78 | 31 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 8% | 14.93 | 72 / 929 | 0% | 0 | 0 / 0 |
| muscle | 6% | 4.17 | 45 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 4% | 0.05 | 3 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0019556 | Biological process | L-histidine catabolic process to glutamate and formamide |
| GO_0007010 | Biological process | cytoskeleton organization |
| GO_0019557 | Biological process | L-histidine catabolic process to glutamate and formate |
| GO_0006760 | Biological process | folic acid-containing compound metabolic process |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005814 | Cellular component | centriole |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0030868 | Cellular component | smooth endoplasmic reticulum membrane |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005829 | Cellular component | cytosol |
| GO_0005793 | Cellular component | endoplasmic reticulum-Golgi intermediate compartment |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0030412 | Molecular function | formimidoyltetrahydrofolate cyclodeaminase activity |
| GO_0030409 | Molecular function | glutamate formimidoyltransferase activity |
| GO_0008017 | Molecular function | microtubule binding |
| GO_0005542 | Molecular function | folic acid binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | FTCD |
| Protein name | Formimidoyltransferase-cyclodeaminase (EC 2.1.2.5) (EC 4.3.1.4) (Formiminotransferase-cyclodeaminase) FTCD protein (Formimidoyltransferase cyclodeaminase) Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) (LCHC1) [Includes: Glutamate formimidoyltransferase (EC 2.1.2.5) (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) (Formiminotetrahydrofolate cyclodeaminase)] Formimidoyltransferase cyclodeaminase |
| Synonyms | |
| Description | FUNCTION: Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool. .; FUNCTION: Binds and promotes bundling of vimentin filaments originating from the Golgi. . FUNCTION: Binds and promotes bundling of vimentin filaments originating from the Golgi. .; FUNCTION: Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool. . FUNCTION: Binds and promotes bundling of vimentin filaments originating from the Golgi. .; FUNCTION: Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool. . |
| Accessions | ENST00000397746.8 [O95954-1] B7WPK3 A0A0G2JQF2 ENST00000460011.6 ENST00000397748.5 [O95954-2] ENST00000446405.5 ENST00000291670.9 [O95954-1] ENST00000625428.2 H7C315 ENST00000625846.2 ENST00000494498.2 ENST00000625714.2 ENST00000629394.1 O95954 A0A804HKA5 Q49AR5 ENST00000397743.1 |
