Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 19 studies | 54% ± 16% | |
epithelial cell | 5 studies | 45% ± 10% | |
GABAergic neuron | 5 studies | 41% ± 18% | |
astrocyte | 5 studies | 26% ± 8% | |
deuterosomal cell | 4 studies | 25% ± 2% | |
squamous epithelial cell | 4 studies | 35% ± 17% | |
retinal ganglion cell | 4 studies | 46% ± 24% | |
goblet cell | 4 studies | 29% ± 16% | |
endothelial cell | 3 studies | 27% ± 9% | |
club cell | 3 studies | 19% ± 2% | |
type II pneumocyte | 3 studies | 28% ± 8% | |
glutamatergic neuron | 3 studies | 55% ± 12% | |
enterocyte | 3 studies | 20% ± 4% | |
basal cell | 3 studies | 31% ± 8% | |
interneuron | 3 studies | 40% ± 17% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 100% | 2759.01 | 652 / 653 | 96% | 56.83 | 580 / 605 |
ovary | 94% | 776.16 | 169 / 180 | 94% | 21.18 | 404 / 430 |
kidney | 100% | 1304.27 | 89 / 89 | 87% | 27.48 | 788 / 901 |
pancreas | 89% | 532.49 | 291 / 328 | 97% | 32.51 | 172 / 178 |
prostate | 86% | 848.86 | 210 / 245 | 99% | 38.25 | 498 / 502 |
lung | 82% | 1249.83 | 475 / 578 | 98% | 31.89 | 1130 / 1155 |
stomach | 69% | 723.70 | 249 / 359 | 95% | 32.95 | 273 / 286 |
breast | 60% | 628.51 | 276 / 459 | 99% | 50.23 | 1108 / 1118 |
esophagus | 51% | 1486.02 | 740 / 1445 | 98% | 38.85 | 180 / 183 |
intestine | 44% | 1072.29 | 425 / 966 | 98% | 35.82 | 515 / 527 |
adrenal gland | 97% | 1019.38 | 251 / 258 | 37% | 6.31 | 85 / 230 |
bladder | 38% | 380.67 | 8 / 21 | 95% | 31.86 | 480 / 504 |
brain | 93% | 1838.40 | 2454 / 2642 | 32% | 6.44 | 228 / 705 |
uterus | 26% | 208.28 | 45 / 170 | 88% | 29.14 | 404 / 459 |
tonsil | 0% | 0 | 0 / 0 | 100% | 31.75 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 13.47 | 1 / 1 |
skin | 72% | 2306.48 | 1305 / 1809 | 5% | 0.63 | 22 / 472 |
liver | 2% | 7.56 | 4 / 226 | 22% | 4.35 | 90 / 406 |
adipose | 15% | 88.97 | 186 / 1204 | 0% | 0 | 0 / 0 |
spleen | 7% | 28.76 | 18 / 241 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 5% | 0.63 | 4 / 80 |
heart | 1% | 2.42 | 5 / 861 | 0% | 0 | 0 / 0 |
muscle | 0% | 1.02 | 2 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 0% | 1.64 | 2 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 1.57 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007165 | Biological process | signal transduction |
GO_0140042 | Biological process | lipid droplet formation |
GO_0007602 | Biological process | phototransduction |
GO_0006657 | Biological process | CDP-choline pathway |
GO_0045600 | Biological process | positive regulation of fat cell differentiation |
GO_0006661 | Biological process | phosphatidylinositol biosynthetic process |
GO_0016024 | Biological process | CDP-diacylglycerol biosynthetic process |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0016020 | Cellular component | membrane |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0004142 | Molecular function | diacylglycerol cholinephosphotransferase activity |
GO_0004605 | Molecular function | phosphatidate cytidylyltransferase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | CDS1 |
Protein name | CDP-diacylglycerol synthase 1 Phosphatidate cytidylyltransferase 1 (EC 2.7.7.41) (CDP-DAG synthase 1) (CDP-DG synthase 1) (CDP-diacylglycerol synthase 1) (CDS 1) (CDP-diglyceride pyrophosphorylase 1) (CDP-diglyceride synthase 1) (CTP:phosphatidate cytidylyltransferase 1) |
Synonyms | CDS |
Description | FUNCTION: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol . Exhibits almost no acyl chain preference for PA, showing no discrimination for the sn-1/sn-2 acyl chain composition of PAs . Plays an important role in regulating the growth of lipid droplets which are storage organelles at the center of lipid and energy homeostasis . Positively regulates the differentiation and development of adipocytes (By similarity). . |
Accessions | Q92903 D6RGC8 ENST00000295887.6 ENST00000511298.1 |