SUMF2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	19 studies	20% ± 4%	Explore
regulatory T cell	13 studies	21% ± 3%	Explore
CD4-positive, alpha-beta T cell	12 studies	23% ± 7%	Explore
CD8-positive, alpha-beta T cell	12 studies	22% ± 6%	Explore
endothelial cell	12 studies	23% ± 8%	Explore
plasmacytoid dendritic cell	12 studies	24% ± 7%	Explore
ciliated cell	12 studies	29% ± 15%	Explore
gamma-delta T cell	11 studies	22% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	22% ± 4%	Explore
macrophage	10 studies	22% ± 7%	Explore
epithelial cell	10 studies	33% ± 21%	Explore
fibroblast	10 studies	23% ± 8%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	9 studies	21% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	23% ± 7%	Explore
T cell	9 studies	18% ± 3%	Explore
CD16-negative, CD56-bright natural killer cell, human	8 studies	22% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	7 studies	19% ± 2%	Explore
B cell	7 studies	23% ± 6%	Explore
pericyte	6 studies	20% ± 3%	Explore
astrocyte	6 studies	23% ± 6%	Explore
hematopoietic precursor cell	5 studies	25% ± 11%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	22% ± 4%	Explore
mature NK T cell	5 studies	19% ± 2%	Explore
memory B cell	5 studies	17% ± 2%	Explore
mucosal invariant T cell	5 studies	20% ± 2%	Explore
basal cell	5 studies	32% ± 15%	Explore
T follicular helper cell	5 studies	18% ± 2%	Explore
abnormal cell	5 studies	26% ± 12%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	20% ± 4%	Explore
conventional dendritic cell	4 studies	32% ± 18%	Explore
exhausted T cell	4 studies	20% ± 5%	Explore
type I pneumocyte	4 studies	26% ± 6%	Explore
neuron	4 studies	27% ± 9%	Explore
connective tissue cell	4 studies	24% ± 6%	Explore
naive B cell	4 studies	18% ± 2%	Explore
pancreatic A cell	3 studies	31% ± 14%	Explore
non-classical monocyte	3 studies	35% ± 8%	Explore
plasmablast	3 studies	39% ± 16%	Explore
plasma cell	3 studies	25% ± 1%	Explore
myofibroblast cell	3 studies	21% ± 5%	Explore
endothelial cell of lymphatic vessel	3 studies	20% ± 6%	Explore
GABAergic neuron	3 studies	37% ± 13%	Explore
glutamatergic neuron	3 studies	45% ± 16%	Explore
dendritic cell	3 studies	37% ± 12%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	25% ± 9%	Explore
goblet cell	3 studies	21% ± 6%	Explore
T-helper 1 cell	3 studies	19% ± 3%	Explore
hematopoietic stem cell	3 studies	19% ± 1%	Explore
double negative thymocyte	3 studies	28% ± 10%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	18% ± 1%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	10 studies	20% ± 7%	Explore
brain	6 studies	27% ± 12%	Explore
lung	4 studies	26% ± 9%	Explore
kidney	3 studies	17% ± 1%	Explore
lymph node	3 studies	17% ± 2%	Explore
liver	3 studies	26% ± 11%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	4619.99	180 / 180	100%	95.69	430 / 430
pancreas	100%	4588.92	328 / 328	100%	110.73	178 / 178
lung	100%	5398.39	578 / 578	100%	123.15	1154 / 1155
stomach	100%	4300.79	359 / 359	100%	94.44	285 / 286
skin	100%	5758.00	1809 / 1809	100%	183.94	470 / 472
breast	100%	5091.98	459 / 459	99%	119.14	1112 / 1118
prostate	100%	4876.99	245 / 245	99%	125.53	499 / 502
esophagus	100%	3560.63	1444 / 1445	99%	82.65	182 / 183
intestine	100%	4479.47	966 / 966	99%	105.47	523 / 527
thymus	100%	5461.34	653 / 653	99%	114.76	600 / 605
bladder	100%	4535.00	21 / 21	99%	104.90	497 / 504
brain	98%	2217.70	2600 / 2642	100%	113.80	704 / 705
liver	100%	3258.48	226 / 226	98%	88.37	398 / 406
uterus	100%	4864.44	170 / 170	98%	84.70	448 / 459
kidney	100%	4850.30	89 / 89	98%	105.80	879 / 901
adrenal gland	100%	5849.48	258 / 258	89%	56.41	204 / 230
adipose	100%	4820.72	1204 / 1204	0%	0	0 / 0
blood vessel	100%	5392.45	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	84.85	29 / 29
muscle	100%	2780.34	803 / 803	0%	0	0 / 0
spleen	100%	4776.54	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	70.44	45 / 45
ureter	0%	0	0 / 0	100%	44.49	1 / 1
eye	0%	0	0 / 0	99%	154.98	79 / 80
heart	97%	2039.25	836 / 861	0%	0	0 / 0
peripheral blood	92%	2483.22	859 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0005788	Cellular component	endoplasmic reticulum lumen
GO_0005783	Cellular component	endoplasmic reticulum
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding

IV. Literature review

[source]

Gene name	SUMF2
Protein name	Sulfatase modifying factor 2 Sulfatase modifying factor 2 isoform 2 Epididymis secretory sperm binding protein (Sulfatase modifying factor 2, isoform CRA_e) Sulfatase modifying factor 2 isoform 4 Sulfatase modifying factor 2 isoform 3 Sulfatase modifying factor 2 isoform 1 Inactive C-alpha-formylglycine-generating enzyme 2 (Paralog of formylglycine-generating enzyme) (pFGE) (Sulfatase-modifying factor 2)
Synonyms	DKFZP566I1024 hCG_1736510 UNQ1968/PRO4500 PSEC0171
Description	FUNCTION: Lacks formylglycine generating activity and is unable to convert newly synthesized inactive sulfatases to their active form. Inhibits the activation of sulfatases by SUMF1. .
Accessions	A8MXB9 J3KQJ1 F8WES7 J3QT17 A0A384ME15 ENST00000651586.1 E9PG02 ENST00000413952.7 ENST00000652303.1 ENST00000342190.11 [Q8NBJ7-3] F8WCW9 Q8NBJ7 A0A0S2Z548 ENST00000413756.5 ENST00000438133.5 F8WA42 E9PBT8 ENST00000452216.5 ENST00000451338.1 C9JL30 A0A0S2Z5Q3 ENST00000651354.1 ENST00000395436.7 ENST00000436782.5 F8WEX5 H7C3B2 ENST00000275607.13 [Q8NBJ7-2] ENST00000434526.8 [Q8NBJ7-1] ENST00000395435.7 [Q8NBJ7-5] F8WEV7 C9J660 ENST00000650735.1 A0A494C1B1 A0A0S2Z5C4 Q75LP3 ENST00000423763.5 ENST00000437307.6 ENST00000447501.5

SUMF2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review