GDI1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0034123Biological processpositive regulation of toll-like receptor signaling pathway
GO_0045773Biological processpositive regulation of axon extension
GO_0050771Biological processnegative regulation of axonogenesis
GO_0007165Biological processsignal transduction
GO_0032482Biological processRab protein signal transduction
GO_0016192Biological processvesicle-mediated transport
GO_0090315Biological processnegative regulation of protein targeting to membrane
GO_0015031Biological processprotein transport
GO_0051592Biological processresponse to calcium ion
GO_0030496Cellular componentmidbody
GO_0043209Cellular componentmyelin sheath
GO_0032991Cellular componentprotein-containing complex
GO_0005794Cellular componentGolgi apparatus
GO_0043025Cellular componentneuronal cell body
GO_0005783Cellular componentendoplasmic reticulum
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0099523Cellular componentpresynaptic cytosol
GO_0030424Cellular componentaxon
GO_0005092Molecular functionGDP-dissociation inhibitor activity
GO_0031267Molecular functionsmall GTPase binding
GO_0005096Molecular functionGTPase activator activity
GO_0005515Molecular functionprotein binding
GO_0005093Molecular functionRab GDP-dissociation inhibitor activity

IV. Literature review

[source]
Gene nameGDI1
Protein nameGDP dissociation inhibitor 1
Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1) (Oligophrenin-2) (Protein XAP-4)
Rab GDP dissociation inhibitor
GDP dissociation inhibitor 1 isoform 2
Alternative protein GDI1
SynonymsRABGDIA
OPHN2
GDIL
hCG_2039440
XAP4
DescriptionFUNCTION: Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes. .

FUNCTION: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP. .; FUNCTION: Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes. .

FUNCTION: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP. .; FUNCTION: Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes. .

AccessionsF8WE59
A0A0S2Z3X8
ENST00000415109.5
P31150
A0A0S2Z426
L8EC88
F8WCU0
ENST00000447750.7
ENST00000630693.2
G5E9U5
ENST00000445564.5