Name | Number of supported studies | Average coverage | |
---|---|---|---|
classical monocyte | 7 studies | 30% ± 9% | |
macrophage | 7 studies | 23% ± 5% | |
type I pneumocyte | 6 studies | 21% ± 6% | |
monocyte | 6 studies | 19% ± 4% | |
endothelial cell | 5 studies | 19% ± 2% | |
epithelial cell | 5 studies | 29% ± 5% | |
non-classical monocyte | 4 studies | 33% ± 12% | |
myeloid cell | 3 studies | 22% ± 2% | |
ciliated cell | 3 studies | 21% ± 2% | |
glutamatergic neuron | 3 studies | 33% ± 11% | |
microglial cell | 3 studies | 21% ± 4% | |
dendritic cell | 3 studies | 28% ± 13% | |
basal cell | 3 studies | 27% ± 7% | |
goblet cell | 3 studies | 23% ± 8% | |
transit amplifying cell | 3 studies | 24% ± 11% | |
astrocyte | 3 studies | 18% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 4600.82 | 459 / 459 | 100% | 58.76 | 1118 / 1118 |
esophagus | 100% | 4590.58 | 1445 / 1445 | 100% | 54.04 | 183 / 183 |
lung | 100% | 6245.25 | 578 / 578 | 100% | 67.61 | 1155 / 1155 |
skin | 100% | 5144.30 | 1809 / 1809 | 100% | 70.44 | 472 / 472 |
intestine | 100% | 6372.76 | 966 / 966 | 100% | 59.41 | 526 / 527 |
bladder | 100% | 6320.67 | 21 / 21 | 100% | 57.70 | 503 / 504 |
prostate | 100% | 5356.49 | 245 / 245 | 100% | 52.33 | 501 / 502 |
uterus | 100% | 5753.01 | 170 / 170 | 100% | 60.04 | 458 / 459 |
kidney | 100% | 4375.49 | 89 / 89 | 100% | 57.31 | 899 / 901 |
pancreas | 100% | 2288.15 | 327 / 328 | 100% | 93.56 | 178 / 178 |
thymus | 100% | 4331.33 | 653 / 653 | 100% | 47.88 | 603 / 605 |
stomach | 100% | 5299.20 | 359 / 359 | 100% | 59.11 | 285 / 286 |
ovary | 100% | 4142.18 | 180 / 180 | 99% | 29.24 | 424 / 430 |
brain | 98% | 2099.83 | 2578 / 2642 | 100% | 45.01 | 705 / 705 |
adrenal gland | 100% | 4275.64 | 258 / 258 | 97% | 33.27 | 224 / 230 |
liver | 100% | 2295.00 | 226 / 226 | 81% | 20.81 | 328 / 406 |
adipose | 100% | 5066.63 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 74.38 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 43.38 | 29 / 29 |
muscle | 100% | 4950.91 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 5426.32 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 51.35 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 142.41 | 1 / 1 |
blood vessel | 100% | 4226.77 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 99% | 3079.68 | 850 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 4719.17 | 916 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0072659 | Biological process | protein localization to plasma membrane |
GO_0009895 | Biological process | negative regulation of catabolic process |
GO_0050847 | Biological process | progesterone receptor signaling pathway |
GO_0150106 | Biological process | regulation of protein localization to cell-cell junction |
GO_0018230 | Biological process | peptidyl-L-cysteine S-palmitoylation |
GO_0006612 | Biological process | protein targeting to membrane |
GO_0044381 | Biological process | glucose import in response to insulin stimulus |
GO_1902044 | Biological process | regulation of Fas signaling pathway |
GO_0008277 | Biological process | regulation of G protein-coupled receptor signaling pathway |
GO_0043401 | Biological process | steroid hormone receptor signaling pathway |
GO_0018345 | Biological process | protein palmitoylation |
GO_1903076 | Biological process | regulation of protein localization to plasma membrane |
GO_0030521 | Biological process | androgen receptor signaling pathway |
GO_0030859 | Biological process | polarized epithelial cell differentiation |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0000139 | Cellular component | Golgi membrane |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0019705 | Molecular function | protein-cysteine S-myristoyltransferase activity |
GO_0016409 | Molecular function | palmitoyltransferase activity |
GO_0019706 | Molecular function | protein-cysteine S-palmitoyltransferase activity |
GO_0140439 | Molecular function | protein-cysteine S-stearoyltransferase activity |
Gene name | ZDHHC7 |
Protein name | Palmitoyltransferase (EC 2.3.1.225) Palmitoyltransferase ZDHHC7 (EC 2.3.1.225) (Acyltransferase ZDHHC7) (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 7) (DHHC-7) Zinc finger DHHC-type palmitoyltransferase 7 |
Synonyms | |
Description | FUNCTION: Golgi-localized palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and therefore functions in several unrelated biological processes . Has no stringent fatty acid selectivity and in addition to palmitate can also transfer onto target proteins myristate from tetradecanoyl-CoA and stearate from octadecanoyl-CoA (By similarity). Palmitoylates sex steroid hormone receptors, including ESR1, PGR and AR, thereby regulating their targeting to the plasma membrane and their function in rapid intracellular signaling upon binding of sex hormones . Palmitoylates GNAQ, a heterotrimeric G protein, regulating its dynamic localization at the plasma membrane and is thereby involved in GNAQ-dependent G protein-coupled receptor signaling pathways . Functions also in ligand-induced cell death by regulating the FAS signaling pathway through the palmitoylation and stabilization of the receptor at the plasma membrane . In epithelial cells, palmitoylates SCRIB and regulates its localization to the plasma membrane, regulating indirectly cell polarity and differentiation . Also palmitoylates JAM3 and promotes its expression at tight junctions and regulates its function in cell migration . Palmitoylates the glucose transporter GLUT4/SLC2A4 and controls the insulin-dependent translocation of GLUT4 to the plasma membrane (By similarity). In brain, could also palmitoylate SNAP25 and DLG4/PSD95 (By similarity). Could also palmitoylate DNAJC5 and regulate its localization to the Golgi membrane (By similarity). Could also palmitoylate NCDN (By similarity). May play a role in follicle stimulation hormone (FSH) activation of testicular Sertoli cells (By similarity). . |
Accessions | ENST00000564466.5 [Q9NXF8-2] ENST00000313732.9 [Q9NXF8-1] ENST00000569017.1 Q9NXF8 H3BMI0 H3BNQ9 ENST00000566909.1 ENST00000344861.9 [Q9NXF8-2] |