Tissue | GTEx Coverage  | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 4286.81 | 652 / 653 | 99% | 11.71 | 599 / 605 |
| esophagus | 98% | 7222.15 | 1423 / 1445 | 99% | 15.52 | 182 / 183 |
| intestine | 100% | 4462.55 | 963 / 966 | 98% | 11.82 | 517 / 527 |
| ovary | 100% | 7969.63 | 180 / 180 | 98% | 10.25 | 420 / 430 |
| brain | 98% | 5282.43 | 2581 / 2642 | 100% | 22.37 | 704 / 705 |
| breast | 100% | 9866.30 | 459 / 459 | 96% | 11.65 | 1068 / 1118 |
| lung | 99% | 4524.80 | 574 / 578 | 96% | 11.64 | 1107 / 1155 |
| adrenal gland | 97% | 3893.17 | 251 / 258 | 97% | 24.88 | 223 / 230 |
| skin | 93% | 3605.15 | 1684 / 1809 | 99% | 16.19 | 466 / 472 |
| prostate | 99% | 3916.69 | 242 / 245 | 91% | 6.28 | 458 / 502 |
| uterus | 99% | 4838.54 | 169 / 170 | 88% | 8.48 | 406 / 459 |
| stomach | 86% | 3142.68 | 308 / 359 | 99% | 11.64 | 283 / 286 |
| liver | 97% | 3693.48 | 220 / 226 | 86% | 8.85 | 349 / 406 |
| bladder | 100% | 5377.62 | 21 / 21 | 82% | 7.45 | 412 / 504 |
| kidney | 93% | 2551.75 | 83 / 89 | 86% | 6.57 | 776 / 901 |
| pancreas | 51% | 1026.08 | 167 / 328 | 93% | 12.61 | 165 / 178 |
| muscle | 100% | 29504.99 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 3957.24 | 241 / 241 | 0% | 0 | 0 / 0 |
| adipose | 100% | 9669.90 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 3489.75 | 1319 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 16.63 | 28 / 29 |
| eye | 0% | 0 | 0 / 0 | 95% | 13.81 | 76 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 89% | 7.30 | 40 / 45 |
| heart | 88% | 3136.60 | 761 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 39% | 1345.65 | 361 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0032869 | Biological process | cellular response to insulin stimulus |
| GO_0006642 | Biological process | triglyceride mobilization |
| GO_0031642 | Biological process | negative regulation of myelination |
| GO_0007077 | Biological process | mitotic nuclear membrane disassembly |
| GO_0031100 | Biological process | animal organ regeneration |
| GO_0019432 | Biological process | triglyceride biosynthetic process |
| GO_0045740 | Biological process | positive regulation of DNA replication |
| GO_0009062 | Biological process | fatty acid catabolic process |
| GO_0120162 | Biological process | positive regulation of cold-induced thermogenesis |
| GO_0006654 | Biological process | phosphatidic acid biosynthetic process |
| GO_0046337 | Biological process | phosphatidylethanolamine metabolic process |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005635 | Cellular component | nuclear envelope |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005741 | Cellular component | mitochondrial outer membrane |
| GO_0031965 | Cellular component | nuclear membrane |
| GO_0005634 | Cellular component | nucleus |
| GO_0008195 | Molecular function | phosphatidate phosphatase activity |
| GO_0003713 | Molecular function | transcription coactivator activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | LPIN1 |
| Protein name | Lipin 1 Phosphatidate phosphatase LPIN1 (EC 3.1.3.4) (Lipin-1) |
| Synonyms | KIAA0188 |
| Description | FUNCTION: Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis and therefore controls the metabolism of fatty acids at different levels . Is involved in adipocyte differentiation (By similarity). Acts also as nuclear transcriptional coactivator for PPARGC1A/PPARA regulatory pathway to modulate lipid metabolism gene expression (By similarity). Recruited at the mitochondrion outer membrane and is involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol (By similarity). . |
| Accessions | ENST00000256720.6 [Q14693-1] ENST00000396098.5 [Q14693-6] A0A0A0MS66 C9IYP2 ENST00000423495.1 ENST00000396099.5 ENST00000441684.5 ENST00000449576.6 [Q14693-7] Q14693 ENST00000674199.1 [Q14693-3] ENST00000425416.6 [Q14693-2] C9J278 ENST00000454151.2 ENST00000396097.5 [Q14693-5] H7C3T1 |
