TMEM203 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007283Biological processspermatogenesis
GO_0006874Biological processintracellular calcium ion homeostasis
GO_0005783Cellular componentendoplasmic reticulum
GO_0005765Cellular componentlysosomal membrane
GO_0005793Cellular componentendoplasmic reticulum-Golgi intermediate compartment
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTMEM203
Protein nameTransmembrane protein 203
Synonyms
DescriptionFUNCTION: Involved in the regulation of cellular calcium homeotasis . Required for spermatogenesis . Acts as a regulator of STING-mediated inflammatory signaling in macrophages . Forms a complex with STING, promoting the activity of TBK1 kinase and the transcription factor IRF3, leading to activation of type I interferon expression (By similarity). .

AccessionsENST00000343666.6
Q969S6