KCNIP3 | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte precursor cell	8 studies	33% ± 15%	Explore
glutamatergic neuron	3 studies	45% ± 22%	Explore
astrocyte	3 studies	21% ± 5%	Explore

Name	Number of supported studies	Average coverage
brain	4 studies	29% ± 14%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	3069.64	653 / 653	98%	21.12	590 / 605
brain	99%	2541.40	2620 / 2642	95%	32.97	673 / 705
skin	97%	788.91	1763 / 1809	83%	9.00	390 / 472
ovary	99%	1180.18	179 / 180	79%	6.06	338 / 430
kidney	100%	1104.40	89 / 89	72%	9.40	650 / 901
uterus	99%	1354.19	169 / 170	46%	3.69	212 / 459
prostate	100%	1358.27	244 / 245	42%	1.35	209 / 502
breast	97%	729.67	446 / 459	42%	2.12	473 / 1118
bladder	100%	1085.71	21 / 21	14%	0.65	71 / 504
esophagus	77%	915.09	1108 / 1445	34%	1.35	62 / 183
stomach	85%	549.29	305 / 359	16%	0.75	45 / 286
eye	0%	0	0 / 0	100%	16.54	80 / 80
blood vessel	99%	902.91	1322 / 1335	0%	0	0 / 0
adipose	96%	766.12	1151 / 1204	0%	0	0 / 0
intestine	84%	790.84	814 / 966	6%	0.24	32 / 527
lung	60%	241.04	348 / 578	25%	1.06	285 / 1155
heart	83%	431.11	714 / 861	0%	0	0 / 0
spleen	71%	282.72	171 / 241	0%	0	0 / 0
adrenal gland	21%	72.48	55 / 258	32%	3.08	74 / 230
pancreas	33%	108.20	107 / 328	15%	0.49	26 / 178
tonsil	0%	0	0 / 0	42%	1.76	19 / 45
liver	10%	33.54	23 / 226	24%	1.14	99 / 406
muscle	4%	14.38	33 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007165	Biological process	signal transduction
GO_0006915	Biological process	apoptotic process
GO_0072659	Biological process	protein localization to plasma membrane
GO_1901379	Biological process	regulation of potassium ion transmembrane transport
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0071805	Biological process	potassium ion transmembrane transport
GO_0008076	Cellular component	voltage-gated potassium channel complex
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005829	Cellular component	cytosol
GO_0005794	Cellular component	Golgi apparatus
GO_0005886	Cellular component	plasma membrane
GO_0005634	Cellular component	nucleus
GO_0005267	Molecular function	potassium channel activity
GO_0000978	Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0015459	Molecular function	potassium channel regulator activity
GO_0005509	Molecular function	calcium ion binding
GO_0005515	Molecular function	protein binding
GO_0001227	Molecular function	DNA-binding transcription repressor activity, RNA polymerase II-specific

Gene name	KCNIP3
Protein name	Calsenilin (A-type potassium channel modulatory protein 3) (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (KChIP3) Potassium voltage-gated channel interacting protein 3
Synonyms	CSEN KCHIP3 DREAM
Description	FUNCTION: Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception (By similarity). .; FUNCTION: Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels, such as KCND2/Kv4.2 and KCND3/Kv4.3. Modulates channel expression at the cell membrane, gating characteristics, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. .; FUNCTION: May play a role in the regulation of PSEN2 proteolytic processing and apoptosis. Together with PSEN2 involved in modulation of amyloid-beta formation. .
Accessions	Q9Y2W7 ENST00000698060.1 ENST00000295225.10 [Q9Y2W7-1] ENST00000468529.1 [Q9Y2W7-3] A0A8V8TMV8

KCNIP3 report