Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| adipocyte | 10 studies | 58% ± 20% | |
| type I pneumocyte | 9 studies | 29% ± 8% | |
| endothelial cell | 8 studies | 24% ± 7% | |
| epithelial cell | 6 studies | 30% ± 10% | |
| type II pneumocyte | 6 studies | 33% ± 10% | |
| microglial cell | 5 studies | 23% ± 7% | |
| endothelial cell of lymphatic vessel | 5 studies | 23% ± 4% | |
| astrocyte | 5 studies | 27% ± 11% | |
| glutamatergic neuron | 5 studies | 48% ± 22% | |
| ciliated cell | 4 studies | 21% ± 2% | |
| GABAergic neuron | 4 studies | 43% ± 15% | |
| oligodendrocyte precursor cell | 4 studies | 24% ± 7% | |
| club cell | 4 studies | 30% ± 10% | |
| goblet cell | 4 studies | 26% ± 9% | |
| interneuron | 4 studies | 38% ± 22% | |
| oligodendrocyte | 4 studies | 27% ± 6% | |
| hepatocyte | 3 studies | 38% ± 16% | |
| fibroblast | 3 studies | 18% ± 0% | |
| macrophage | 3 studies | 19% ± 2% | |
| basal cell | 3 studies | 24% ± 5% | |
| transit amplifying cell | 3 studies | 30% ± 12% | |
| neuron | 3 studies | 29% ± 6% | |
| erythroblast | 3 studies | 20% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 6370.78 | 459 / 459 | 100% | 49.32 | 1118 / 1118 |
| esophagus | 100% | 2471.22 | 1445 / 1445 | 100% | 44.23 | 183 / 183 |
| lung | 100% | 3461.94 | 578 / 578 | 100% | 49.41 | 1155 / 1155 |
| ovary | 100% | 3025.69 | 180 / 180 | 100% | 34.68 | 430 / 430 |
| intestine | 100% | 2513.37 | 966 / 966 | 100% | 39.93 | 526 / 527 |
| uterus | 100% | 2483.86 | 170 / 170 | 100% | 30.20 | 458 / 459 |
| stomach | 100% | 1920.33 | 358 / 359 | 100% | 40.70 | 286 / 286 |
| prostate | 100% | 2090.44 | 245 / 245 | 100% | 39.49 | 500 / 502 |
| brain | 99% | 2210.85 | 2627 / 2642 | 100% | 35.87 | 704 / 705 |
| bladder | 100% | 2866.24 | 21 / 21 | 99% | 33.18 | 500 / 504 |
| thymus | 100% | 2104.33 | 651 / 653 | 99% | 27.60 | 601 / 605 |
| liver | 100% | 1746.40 | 226 / 226 | 99% | 21.27 | 402 / 406 |
| pancreas | 99% | 1380.95 | 325 / 328 | 99% | 32.96 | 176 / 178 |
| skin | 100% | 3647.01 | 1809 / 1809 | 98% | 33.26 | 461 / 472 |
| kidney | 100% | 1414.51 | 89 / 89 | 97% | 22.93 | 873 / 901 |
| adrenal gland | 100% | 2155.80 | 258 / 258 | 96% | 22.49 | 220 / 230 |
| adipose | 100% | 7944.42 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 3410.69 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 19.22 | 29 / 29 |
| spleen | 100% | 1376.25 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 24.51 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 16.95 | 1 / 1 |
| muscle | 100% | 2297.81 | 802 / 803 | 0% | 0 | 0 / 0 |
| heart | 94% | 1616.41 | 813 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 86% | 11.77 | 69 / 80 |
| peripheral blood | 42% | 892.12 | 387 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0017187 | Biological process | peptidyl-glutamic acid carboxylation |
| GO_0034599 | Biological process | cellular response to oxidative stress |
| GO_0042373 | Biological process | vitamin K metabolic process |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0047057 | Molecular function | vitamin-K-epoxide reductase (warfarin-sensitive) activity |
| GO_0048038 | Molecular function | quinone binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | VKORC1L1 |
| Protein name | Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1-like protein 1) (EC 1.17.4.4) vitamin-K-epoxide reductase (warfarin-sensitive) (EC 1.17.4.4) |
| Synonyms | |
| Description | FUNCTION: Involved in vitamin K metabolism. Can reduce inactive vitamin K 2,3-epoxide to active vitamin K, and may contribute to vitamin K-mediated protection against oxidative stress. Plays a role in vitamin K-dependent gamma-carboxylation of Glu residues in target proteins. . |
| Accessions | Q8N0U8 ENST00000648179.1 [Q8N0U8-1] ENST00000434382.2 [Q8N0U8-2] A0A3B3ISV4 ENST00000648187.1 ENST00000360768.5 [Q8N0U8-1] |