Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 16 studies | 37% ± 15% | |
| endothelial cell | 11 studies | 24% ± 11% | |
| microglial cell | 9 studies | 26% ± 10% | |
| interneuron | 7 studies | 29% ± 20% | |
| astrocyte | 7 studies | 24% ± 9% | |
| macrophage | 6 studies | 24% ± 6% | |
| oligodendrocyte precursor cell | 6 studies | 23% ± 7% | |
| glutamatergic neuron | 5 studies | 33% ± 16% | |
| epithelial cell | 5 studies | 25% ± 5% | |
| retina horizontal cell | 5 studies | 30% ± 4% | |
| GABAergic neuron | 5 studies | 31% ± 14% | |
| granule cell | 3 studies | 20% ± 3% | |
| neuron | 3 studies | 28% ± 5% | |
| ciliated cell | 3 studies | 21% ± 2% | |
| dendritic cell | 3 studies | 22% ± 6% | |
| endothelial cell of lymphatic vessel | 3 studies | 17% ± 1% | |
| transit amplifying cell | 3 studies | 23% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 13 studies | 29% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 14772.25 | 2642 / 2642 | 100% | 50.07 | 705 / 705 |
| pancreas | 100% | 4608.48 | 328 / 328 | 100% | 21.60 | 178 / 178 |
| esophagus | 100% | 5252.07 | 1444 / 1445 | 100% | 21.26 | 183 / 183 |
| thymus | 100% | 5277.12 | 652 / 653 | 100% | 21.25 | 605 / 605 |
| prostate | 100% | 6135.64 | 245 / 245 | 100% | 19.05 | 501 / 502 |
| uterus | 100% | 6864.42 | 170 / 170 | 100% | 20.84 | 458 / 459 |
| ovary | 100% | 5901.43 | 180 / 180 | 100% | 28.33 | 429 / 430 |
| intestine | 100% | 6007.91 | 966 / 966 | 99% | 19.19 | 524 / 527 |
| kidney | 100% | 4657.29 | 89 / 89 | 99% | 18.57 | 894 / 901 |
| bladder | 100% | 5950.67 | 21 / 21 | 99% | 19.64 | 500 / 504 |
| breast | 100% | 6007.99 | 459 / 459 | 99% | 19.78 | 1108 / 1118 |
| stomach | 100% | 4512.14 | 358 / 359 | 99% | 18.81 | 284 / 286 |
| skin | 100% | 3739.66 | 1801 / 1809 | 99% | 19.99 | 469 / 472 |
| lung | 99% | 5388.62 | 575 / 578 | 99% | 19.54 | 1148 / 1155 |
| adrenal gland | 100% | 5346.99 | 258 / 258 | 99% | 20.66 | 227 / 230 |
| liver | 70% | 1280.32 | 158 / 226 | 87% | 8.32 | 355 / 406 |
| adipose | 100% | 6442.04 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 26.24 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 11.10 | 29 / 29 |
| muscle | 100% | 9171.73 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 7135.56 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 14.63 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 20.20 | 1 / 1 |
| blood vessel | 100% | 5479.10 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| heart | 98% | 4316.70 | 846 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 36% | 672.73 | 337 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006915 | Biological process | apoptotic process |
| GO_0034497 | Biological process | protein localization to phagophore assembly site |
| GO_0072659 | Biological process | protein localization to plasma membrane |
| GO_0032469 | Biological process | endoplasmic reticulum calcium ion homeostasis |
| GO_0000045 | Biological process | autophagosome assembly |
| GO_1990456 | Biological process | mitochondrion-endoplasmic reticulum membrane tethering |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0005515 | Molecular function | protein binding |
| GO_0044325 | Molecular function | transmembrane transporter binding |
| Gene name | PACS2 |
| Protein name | Phosphofurin acidic cluster sorting protein 2 Phosphofurin acidic cluster sorting protein 2 (PACS-2) (PACS1-like protein) |
| Synonyms | PACS1L KIAA0602 |
| Description | FUNCTION: Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptotic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments. . |
| Accessions | ENST00000447393.6 [Q86VP3-2] ENST00000686461.1 A0A8I5KQA5 ENST00000547217.5 F8VW41 ENST00000325438.12 [Q86VP3-1] ENST00000685365.1 ENST00000430725.6 [Q86VP3-4] Q86VP3 A0A8I5QJV1 |