Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 16 studies | 37% ± 15% | |
endothelial cell | 11 studies | 24% ± 11% | |
microglial cell | 9 studies | 26% ± 10% | |
interneuron | 7 studies | 29% ± 20% | |
astrocyte | 7 studies | 24% ± 9% | |
macrophage | 6 studies | 24% ± 6% | |
oligodendrocyte precursor cell | 6 studies | 23% ± 7% | |
glutamatergic neuron | 5 studies | 33% ± 16% | |
epithelial cell | 5 studies | 25% ± 5% | |
retina horizontal cell | 5 studies | 30% ± 4% | |
GABAergic neuron | 5 studies | 31% ± 14% | |
granule cell | 3 studies | 20% ± 3% | |
neuron | 3 studies | 28% ± 5% | |
ciliated cell | 3 studies | 21% ± 2% | |
dendritic cell | 3 studies | 22% ± 6% | |
endothelial cell of lymphatic vessel | 3 studies | 17% ± 1% | |
transit amplifying cell | 3 studies | 23% ± 9% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 13 studies | 29% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 14772.25 | 2642 / 2642 | 100% | 50.07 | 705 / 705 |
pancreas | 100% | 4608.48 | 328 / 328 | 100% | 21.60 | 178 / 178 |
esophagus | 100% | 5252.07 | 1444 / 1445 | 100% | 21.26 | 183 / 183 |
thymus | 100% | 5277.12 | 652 / 653 | 100% | 21.25 | 605 / 605 |
prostate | 100% | 6135.64 | 245 / 245 | 100% | 19.05 | 501 / 502 |
uterus | 100% | 6864.42 | 170 / 170 | 100% | 20.84 | 458 / 459 |
ovary | 100% | 5901.43 | 180 / 180 | 100% | 28.33 | 429 / 430 |
intestine | 100% | 6007.91 | 966 / 966 | 99% | 19.19 | 524 / 527 |
kidney | 100% | 4657.29 | 89 / 89 | 99% | 18.57 | 894 / 901 |
bladder | 100% | 5950.67 | 21 / 21 | 99% | 19.64 | 500 / 504 |
breast | 100% | 6007.99 | 459 / 459 | 99% | 19.78 | 1108 / 1118 |
stomach | 100% | 4512.14 | 358 / 359 | 99% | 18.81 | 284 / 286 |
skin | 100% | 3739.66 | 1801 / 1809 | 99% | 19.99 | 469 / 472 |
lung | 99% | 5388.62 | 575 / 578 | 99% | 19.54 | 1148 / 1155 |
adrenal gland | 100% | 5346.99 | 258 / 258 | 99% | 20.66 | 227 / 230 |
liver | 70% | 1280.32 | 158 / 226 | 87% | 8.32 | 355 / 406 |
adipose | 100% | 6442.04 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 26.24 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 11.10 | 29 / 29 |
muscle | 100% | 9171.73 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 7135.56 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 14.63 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 20.20 | 1 / 1 |
blood vessel | 100% | 5479.10 | 1333 / 1335 | 0% | 0 | 0 / 0 |
heart | 98% | 4316.70 | 846 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 36% | 672.73 | 337 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006915 | Biological process | apoptotic process |
GO_0034497 | Biological process | protein localization to phagophore assembly site |
GO_0072659 | Biological process | protein localization to plasma membrane |
GO_0032469 | Biological process | endoplasmic reticulum calcium ion homeostasis |
GO_0000045 | Biological process | autophagosome assembly |
GO_1990456 | Biological process | mitochondrion-endoplasmic reticulum membrane tethering |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0005739 | Cellular component | mitochondrion |
GO_0005515 | Molecular function | protein binding |
GO_0044325 | Molecular function | transmembrane transporter binding |
Gene name | PACS2 |
Protein name | Phosphofurin acidic cluster sorting protein 2 Phosphofurin acidic cluster sorting protein 2 (PACS-2) (PACS1-like protein) |
Synonyms | PACS1L KIAA0602 |
Description | FUNCTION: Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptotic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments. . |
Accessions | ENST00000447393.6 [Q86VP3-2] ENST00000686461.1 A0A8I5KQA5 ENST00000547217.5 F8VW41 ENST00000325438.12 [Q86VP3-1] ENST00000685365.1 ENST00000430725.6 [Q86VP3-4] Q86VP3 A0A8I5QJV1 |