I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| retinal rod cell | 8 studies | 41% ± 23% | |
| enterocyte | 6 studies | 54% ± 20% | |
| epithelial cell | 5 studies | 33% ± 12% | |
| hepatocyte | 3 studies | 31% ± 10% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| retinal rod cell | 8 studies | 41% ± 23% | |
| enterocyte | 6 studies | 54% ± 20% | |
| epithelial cell | 5 studies | 33% ± 12% | |
| hepatocyte | 3 studies | 31% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 16570.77 | 226 / 226 | 97% | 362.90 | 392 / 406 |
| prostate | 96% | 1711.25 | 234 / 245 | 99% | 147.09 | 496 / 502 |
| adrenal gland | 100% | 6775.77 | 258 / 258 | 81% | 133.19 | 187 / 230 |
| breast | 93% | 1574.77 | 428 / 459 | 82% | 124.88 | 918 / 1118 |
| brain | 100% | 1025.94 | 2633 / 2642 | 70% | 23.88 | 497 / 705 |
| pancreas | 100% | 1287.42 | 328 / 328 | 70% | 35.24 | 124 / 178 |
| thymus | 98% | 534.30 | 638 / 653 | 63% | 22.91 | 379 / 605 |
| skin | 87% | 503.13 | 1574 / 1809 | 61% | 30.60 | 290 / 472 |
| bladder | 71% | 690.10 | 15 / 21 | 70% | 64.76 | 352 / 504 |
| stomach | 66% | 212.78 | 238 / 359 | 71% | 46.50 | 202 / 286 |
| intestine | 58% | 1020.76 | 561 / 966 | 70% | 41.26 | 370 / 527 |
| kidney | 99% | 1500.35 | 88 / 89 | 13% | 4.77 | 118 / 901 |
| uterus | 75% | 276.96 | 127 / 170 | 37% | 18.72 | 168 / 459 |
| ovary | 90% | 611.79 | 162 / 180 | 18% | 6.07 | 76 / 430 |
| esophagus | 50% | 406.49 | 716 / 1445 | 55% | 28.83 | 101 / 183 |
| eye | 0% | 0 | 0 / 0 | 100% | 69.76 | 80 / 80 |
| ureter | 0% | 0 | 0 / 0 | 100% | 54.08 | 1 / 1 |
| lung | 31% | 89.44 | 179 / 578 | 45% | 25.24 | 519 / 1155 |
| adipose | 75% | 479.24 | 907 / 1204 | 0% | 0 | 0 / 0 |
| heart | 37% | 96.75 | 318 / 861 | 0% | 0 | 0 / 0 |
| spleen | 21% | 66.05 | 50 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 13% | 3.87 | 6 / 45 |
| blood vessel | 13% | 38.33 | 177 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 11% | 27.64 | 87 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 7% | 26.50 | 67 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0007029 | Biological process | endoplasmic reticulum organization |
| GO_0032386 | Biological process | regulation of intracellular transport |
| GO_0050908 | Biological process | detection of light stimulus involved in visual perception |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0001917 | Cellular component | photoreceptor inner segment |
| GO_0030665 | Cellular component | clathrin-coated vesicle membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| Gene name | REEP6 |
| Protein name | Receptor expression-enhancing protein Receptor expression-enhancing protein 6 (Polyposis locus protein 1-like 1) |
| Synonyms | DP1L1 C19orf32 |
| Description | FUNCTION: Required for correct function and survival of retinal photoreceptors . Required for retinal development (By similarity). In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis (By similarity). May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane (By similarity). . |
| Accessions | ENST00000395479.10 [Q96HR9-1] A0A1L5BXV2 Q96HR9 ENST00000395484.4 A8MXN1 ENST00000233596.8 [Q96HR9-2] |
