Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 14 studies | 37% ± 16% | |
| oligodendrocyte precursor cell | 13 studies | 43% ± 19% | |
| macrophage | 12 studies | 33% ± 15% | |
| glutamatergic neuron | 11 studies | 83% ± 15% | |
| GABAergic neuron | 10 studies | 69% ± 24% | |
| neuron | 10 studies | 60% ± 18% | |
| astrocyte | 9 studies | 35% ± 17% | |
| endothelial cell | 8 studies | 44% ± 19% | |
| amacrine cell | 8 studies | 49% ± 21% | |
| microglial cell | 7 studies | 33% ± 15% | |
| retinal ganglion cell | 7 studies | 75% ± 23% | |
| pericyte | 6 studies | 27% ± 17% | |
| retina horizontal cell | 6 studies | 56% ± 23% | |
| dendritic cell | 6 studies | 37% ± 8% | |
| interneuron | 5 studies | 80% ± 19% | |
| retinal cone cell | 5 studies | 52% ± 26% | |
| monocyte | 5 studies | 36% ± 9% | |
| myeloid cell | 5 studies | 32% ± 8% | |
| granule cell | 4 studies | 70% ± 14% | |
| GABAergic amacrine cell | 4 studies | 49% ± 12% | |
| glycinergic amacrine cell | 4 studies | 49% ± 9% | |
| retinal rod cell | 4 studies | 35% ± 12% | |
| mononuclear phagocyte | 3 studies | 27% ± 3% | |
| rod bipolar cell | 3 studies | 33% ± 11% | |
| adipocyte | 3 studies | 26% ± 5% | |
| enteroendocrine cell | 3 studies | 31% ± 11% | |
| alveolar macrophage | 3 studies | 23% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 98% | 29684.69 | 2601 / 2642 | 100% | 187.38 | 704 / 705 |
| prostate | 7% | 184.27 | 18 / 245 | 97% | 28.80 | 486 / 502 |
| breast | 28% | 924.77 | 129 / 459 | 61% | 12.39 | 682 / 1118 |
| spleen | 89% | 2990.59 | 214 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 80% | 5731.34 | 1068 / 1335 | 0% | 0 | 0 / 0 |
| adrenal gland | 5% | 158.31 | 13 / 258 | 73% | 37.55 | 168 / 230 |
| pancreas | 0% | 5.91 | 1 / 328 | 53% | 10.64 | 95 / 178 |
| lymph node | 0% | 0 | 0 / 0 | 48% | 5.71 | 14 / 29 |
| adipose | 41% | 1399.00 | 493 / 1204 | 0% | 0 | 0 / 0 |
| kidney | 0% | 0 | 0 / 89 | 38% | 3.14 | 340 / 901 |
| lung | 7% | 125.43 | 38 / 578 | 29% | 2.25 | 331 / 1155 |
| ovary | 0% | 0 | 0 / 180 | 27% | 2.05 | 118 / 430 |
| skin | 2% | 50.55 | 39 / 1809 | 25% | 3.34 | 119 / 472 |
| uterus | 1% | 38.52 | 2 / 170 | 21% | 3.21 | 98 / 459 |
| intestine | 12% | 272.82 | 118 / 966 | 9% | 1.10 | 50 / 527 |
| stomach | 3% | 65.35 | 12 / 359 | 17% | 1.10 | 48 / 286 |
| thymus | 1% | 14.20 | 5 / 653 | 17% | 1.12 | 105 / 605 |
| tonsil | 0% | 0 | 0 / 0 | 13% | 0.82 | 6 / 45 |
| esophagus | 1% | 25.87 | 18 / 1445 | 10% | 0.85 | 19 / 183 |
| liver | 0% | 0 | 0 / 226 | 10% | 2.01 | 39 / 406 |
| bladder | 0% | 0 | 0 / 21 | 9% | 1.29 | 46 / 504 |
| eye | 0% | 0 | 0 / 0 | 4% | 0.98 | 3 / 80 |
| peripheral blood | 1% | 9.40 | 5 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007420 | Biological process | brain development |
| GO_0071787 | Biological process | endoplasmic reticulum tubular network formation |
| GO_1902430 | Biological process | negative regulation of amyloid-beta formation |
| GO_0030182 | Biological process | neuron differentiation |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0043025 | Cellular component | neuronal cell body |
| GO_0014069 | Cellular component | postsynaptic density |
| GO_0043005 | Cellular component | neuron projection |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0030425 | Cellular component | dendrite |
| GO_0005515 | Molecular function | protein binding |
| Gene name | RTN1 |
| Protein name | Reticulon-1 (Neuroendocrine-specific protein) Reticulon 1 isoform A Reticulon |
| Synonyms | NSP |
| Description | FUNCTION: Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity. . FUNCTION: Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity. . FUNCTION: Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity. . FUNCTION: Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity. . FUNCTION: Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity. . |
| Accessions | ENST00000342503.8 [Q16799-3] Q6IAX4 Q16799 Q2L7A7 Q2NKQ5 A8MT72 ENST00000267484.10 [Q16799-1] ENST00000395090.5 |