CDNF report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CDNF at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CDNF at tissue level.

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0071542Biological processdopaminergic neuron differentiation
GO_0031175Biological processneuron projection development
GO_0005615Cellular componentextracellular space
GO_0005783Cellular componentendoplasmic reticulum
GO_0008083Molecular functiongrowth factor activity

IV. Literature review

[source]
Gene nameCDNF
Protein nameCerebral dopamine neurotrophic factor (ARMET-like protein 1) (Conserved dopamine neurotrophic factor)
SynonymsARMETL1
DescriptionFUNCTION: Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity). .

AccessionsQ49AH0
ENST00000465530.2 [Q49AH0-1]
ENST00000378442.5 [Q49AH0-2]