P3H1 | OmnibusX

Name	Number of supported studies	Average coverage
fibroblast	8 studies	22% ± 5%	Explore
connective tissue cell	4 studies	36% ± 23%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of P3H1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	2042.73	226 / 226	100%	18.26	406 / 406
skin	100%	3398.39	1808 / 1809	100%	47.68	472 / 472
ovary	100%	3127.23	180 / 180	100%	22.58	429 / 430
lung	100%	2947.77	577 / 578	100%	23.00	1154 / 1155
uterus	100%	3069.52	170 / 170	100%	33.22	457 / 459
breast	100%	2412.01	459 / 459	99%	25.89	1112 / 1118
prostate	100%	2342.40	245 / 245	99%	15.32	499 / 502
thymus	100%	2262.07	653 / 653	99%	15.89	601 / 605
bladder	100%	2348.33	21 / 21	99%	22.17	499 / 504
intestine	100%	1874.11	966 / 966	99%	15.73	521 / 527
stomach	99%	1265.01	356 / 359	100%	16.44	285 / 286
adrenal gland	100%	2619.53	258 / 258	98%	16.78	226 / 230
esophagus	99%	1660.31	1429 / 1445	99%	21.30	181 / 183
pancreas	98%	961.17	320 / 328	99%	28.78	177 / 178
kidney	100%	1765.84	89 / 89	95%	18.68	859 / 901
brain	90%	854.52	2375 / 2642	94%	12.13	665 / 705
adipose	100%	2601.73	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	17.64	29 / 29
spleen	100%	3686.12	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	18.67	45 / 45
ureter	0%	0	0 / 0	100%	8.87	1 / 1
blood vessel	100%	2620.33	1334 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	99%	17.52	79 / 80
heart	98%	1295.61	841 / 861	0%	0	0 / 0
peripheral blood	92%	1191.97	855 / 929	0%	0	0 / 0
muscle	67%	424.35	534 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0008285	Biological process	negative regulation of cell population proliferation
GO_0018126	Biological process	protein hydroxylation
GO_0010976	Biological process	positive regulation of neuron projection development
GO_0061077	Biological process	chaperone-mediated protein folding
GO_1901874	Biological process	negative regulation of post-translational protein modification
GO_0006457	Biological process	protein folding
GO_0050821	Biological process	protein stabilization
GO_0060348	Biological process	bone development
GO_0050708	Biological process	regulation of protein secretion
GO_0032963	Biological process	collagen metabolic process
GO_0016020	Cellular component	membrane
GO_0070062	Cellular component	extracellular exosome
GO_0032991	Cellular component	protein-containing complex
GO_0062023	Cellular component	collagen-containing extracellular matrix
GO_0005788	Cellular component	endoplasmic reticulum lumen
GO_0005783	Cellular component	endoplasmic reticulum
GO_0031418	Molecular function	L-ascorbic acid binding
GO_0005506	Molecular function	iron ion binding
GO_0005518	Molecular function	collagen binding
GO_0005515	Molecular function	protein binding
GO_0003674	Molecular function	molecular_function
GO_0019797	Molecular function	procollagen-proline 3-dioxygenase activity

Gene name	P3H1
Protein name	Prolyl 3-hydroxylase 1 (EC 1.14.11.7) (Growth suppressor 1) (Leucine- and proline-enriched proteoglycan 1) (Leprecan-1) Prolyl 3-hydroxylase 1
Synonyms	LEPRE1 PSEC0109 GROS1
Description	FUNCTION: Basement membrane-associated chondroitin sulfate proteoglycan (CSPG). Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens, especially types IV and V. May be involved in the secretory pathway of cells. Has growth suppressive activity in fibroblasts. .
Accessions	ENST00000372526.2 ENST00000296388.10 [Q32P28-1] H7C2W6 ENST00000236040.8 [Q32P28-3] Q32P28 ENST00000397054.7 [Q32P28-4] E2QRI1 ENST00000431412.3

P3H1 report