I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| endothelial cell | 5 studies | 18% ± 2% | |
| epithelial cell | 5 studies | 26% ± 9% | |
| dendritic cell | 3 studies | 19% ± 3% | |
| basal cell | 3 studies | 19% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 5 studies | 18% ± 2% | |
| epithelial cell | 5 studies | 26% ± 9% | |
| dendritic cell | 3 studies | 19% ± 3% | |
| basal cell | 3 studies | 19% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 20% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| bladder | 100% | 2493.48 | 21 / 21 | 100% | 38.80 | 504 / 504 |
| breast | 100% | 2637.22 | 459 / 459 | 100% | 42.07 | 1118 / 1118 |
| lung | 100% | 2390.34 | 578 / 578 | 100% | 51.04 | 1155 / 1155 |
| ovary | 100% | 2442.43 | 180 / 180 | 100% | 34.89 | 430 / 430 |
| uterus | 100% | 2594.09 | 170 / 170 | 100% | 46.28 | 459 / 459 |
| esophagus | 100% | 2205.25 | 1444 / 1445 | 100% | 49.34 | 183 / 183 |
| prostate | 100% | 2751.47 | 245 / 245 | 100% | 26.89 | 501 / 502 |
| stomach | 100% | 1916.92 | 359 / 359 | 100% | 33.87 | 285 / 286 |
| intestine | 100% | 2419.76 | 966 / 966 | 100% | 34.63 | 525 / 527 |
| pancreas | 100% | 1537.60 | 328 / 328 | 99% | 29.84 | 177 / 178 |
| skin | 100% | 3217.93 | 1809 / 1809 | 99% | 36.61 | 469 / 472 |
| thymus | 100% | 2749.15 | 653 / 653 | 99% | 26.57 | 601 / 605 |
| brain | 99% | 1376.57 | 2617 / 2642 | 100% | 32.33 | 705 / 705 |
| kidney | 100% | 1881.11 | 89 / 89 | 99% | 23.31 | 892 / 901 |
| liver | 100% | 2014.87 | 226 / 226 | 99% | 18.83 | 400 / 406 |
| adrenal gland | 100% | 2118.09 | 258 / 258 | 97% | 18.60 | 222 / 230 |
| adipose | 100% | 2598.18 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 33.89 | 29 / 29 |
| muscle | 100% | 2260.70 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 2782.08 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 59.52 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 26.69 | 1 / 1 |
| blood vessel | 100% | 1742.25 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 1479.85 | 854 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 94% | 15.74 | 75 / 80 |
| peripheral blood | 83% | 1239.13 | 768 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0015031 | Biological process | protein transport |
| GO_0051168 | Biological process | nuclear export |
| GO_0000054 | Biological process | ribosomal subunit export from nucleus |
| GO_0015030 | Cellular component | Cajal body |
| GO_0016604 | Cellular component | nuclear body |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0016020 | Cellular component | membrane |
| GO_0005525 | Molecular function | GTP binding |
| GO_0003924 | Molecular function | GTPase activity |
| Gene name | LSG1 |
| Protein name | Large subunit GTPase 1 homolog Large subunit GTPase 1 homolog (hLsg1) (EC 3.6.1.-) Large 60S subunit nuclear export GTPase 1 |
| Synonyms | |
| Description | FUNCTION: GTPase required for the XPO1/CRM1-mediated nuclear export of the 60S ribosomal subunit. Probably acts by mediating the release of NMD3 from the 60S ribosomal subunit after export into the cytoplasm (Probable). . FUNCTION: GTPase required for the XPO1/CRM1-mediated nuclear export of the 60S ribosomal subunit. Probably acts by mediating the release of NMD3 from the 60S ribosomal subunit after export into the cytoplasm. . |
| Accessions | ENST00000265245.10 F8WFC6 ENST00000427461.1 Q9H089 H7C2X7 ENST00000437613.1 |
