Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 32 studies | 37% ± 15% | |
astrocyte | 11 studies | 33% ± 19% | |
endothelial cell of artery | 11 studies | 31% ± 19% | |
endothelial cell of lymphatic vessel | 10 studies | 40% ± 18% | |
pericyte | 10 studies | 30% ± 11% | |
glutamatergic neuron | 10 studies | 41% ± 18% | |
fibroblast | 10 studies | 34% ± 14% | |
vein endothelial cell | 10 studies | 35% ± 24% | |
smooth muscle cell | 9 studies | 31% ± 11% | |
GABAergic neuron | 9 studies | 44% ± 19% | |
adipocyte | 8 studies | 41% ± 9% | |
capillary endothelial cell | 6 studies | 25% ± 9% | |
endothelial cell of vascular tree | 6 studies | 44% ± 22% | |
neuron | 4 studies | 23% ± 6% | |
cardiac muscle cell | 4 studies | 36% ± 5% | |
interneuron | 4 studies | 48% ± 21% | |
glomerular endothelial cell | 3 studies | 26% ± 5% | |
GABAergic interneuron | 3 studies | 40% ± 8% | |
GABAergic amacrine cell | 3 studies | 41% ± 9% | |
neural progenitor cell | 3 studies | 26% ± 14% | |
ependymal cell | 3 studies | 39% ± 18% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 97% | 2922.59 | 174 / 180 | 97% | 17.84 | 415 / 430 |
adrenal gland | 98% | 3331.69 | 254 / 258 | 90% | 14.14 | 208 / 230 |
kidney | 99% | 3562.98 | 88 / 89 | 72% | 10.76 | 645 / 901 |
breast | 100% | 6747.18 | 458 / 459 | 70% | 6.92 | 783 / 1118 |
prostate | 87% | 2459.27 | 214 / 245 | 79% | 4.46 | 399 / 502 |
lung | 96% | 3579.28 | 554 / 578 | 62% | 7.18 | 717 / 1155 |
brain | 69% | 2149.02 | 1833 / 2642 | 85% | 5.24 | 601 / 705 |
esophagus | 82% | 4375.64 | 1192 / 1445 | 70% | 7.88 | 128 / 183 |
uterus | 99% | 3959.95 | 169 / 170 | 50% | 5.43 | 230 / 459 |
thymus | 86% | 1957.00 | 559 / 653 | 61% | 5.19 | 368 / 605 |
skin | 73% | 3819.42 | 1322 / 1809 | 64% | 5.33 | 300 / 472 |
bladder | 100% | 4896.95 | 21 / 21 | 33% | 2.57 | 167 / 504 |
intestine | 87% | 3777.45 | 837 / 966 | 31% | 2.10 | 162 / 527 |
stomach | 59% | 2824.38 | 212 / 359 | 48% | 3.05 | 137 / 286 |
adipose | 100% | 8306.64 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 10339.18 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 9125.22 | 241 / 241 | 0% | 0 | 0 / 0 |
muscle | 99% | 3974.09 | 797 / 803 | 0% | 0 | 0 / 0 |
heart | 97% | 3468.75 | 833 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 81% | 9.83 | 65 / 80 |
pancreas | 5% | 65.39 | 16 / 328 | 66% | 4.08 | 117 / 178 |
tonsil | 0% | 0 | 0 / 0 | 60% | 4.19 | 27 / 45 |
liver | 2% | 26.12 | 5 / 226 | 23% | 1.01 | 92 / 406 |
peripheral blood | 16% | 340.31 | 151 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 10% | 0.22 | 3 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0035269 | Biological process | protein O-linked mannosylation |
GO_0006396 | Biological process | RNA processing |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0016020 | Cellular component | membrane |
GO_0004169 | Molecular function | dolichyl-phosphate-mannose-protein mannosyltransferase activity |
GO_0000030 | Molecular function | mannosyltransferase activity |
Gene name | TMTC1 |
Protein name | Protein O-mannosyl-transferase TMTC1 (EC 2.4.1.109) (Transmembrane O-mannosyltransferase targeting cadherins 1) (Transmembrane and tetratricopeptide repeat-containing 1) Transmembrane O-mannosyltransferase targeting cadherins 1 dolichyl-phosphate-mannose--protein mannosyltransferase (EC 2.4.1.109) |
Synonyms | ARG99 |
Description | FUNCTION: Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O-mannosyl-transferase on other proteins such as PDIA3. . |
Accessions | ENST00000550354.1 ENST00000539277.6 [Q8IUR5-5] F8VXU8 Q8IUR5 ENST00000256062.9 [Q8IUR5-1] F8VTQ9 ENST00000552618.5 H0YIB9 ENST00000551659.6 |