I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| precursor B cell | 6 studies | 58% ± 21% | |
| pro-B cell | 5 studies | 85% ± 9% | |
| B cell | 3 studies | 46% ± 15% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| precursor B cell | 6 studies | 58% ± 21% | |
| pro-B cell | 5 studies | 85% ± 9% | |
| B cell | 3 studies | 46% ± 15% |
Insufficient scRNA-seq data for expression of VPREB1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| spleen | 93% | 14.50 | 225 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 45% | 4.68 | 415 / 929 | 0% | 0 | 0 / 0 |
| intestine | 42% | 4.56 | 408 / 966 | 1% | 0.04 | 7 / 527 |
| stomach | 36% | 2.31 | 128 / 359 | 2% | 0.06 | 5 / 286 |
| lung | 35% | 1.92 | 204 / 578 | 1% | 0.01 | 9 / 1155 |
| thymus | 10% | 0.85 | 66 / 653 | 11% | 1.75 | 66 / 605 |
| breast | 20% | 1.16 | 90 / 459 | 0% | 0.01 | 3 / 1118 |
| bladder | 10% | 0.67 | 2 / 21 | 2% | 0.08 | 11 / 504 |
| kidney | 11% | 1.18 | 10 / 89 | 0% | 0.00 | 3 / 901 |
| liver | 10% | 0.28 | 23 / 226 | 0% | 0.01 | 1 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 10% | 0.75 | 3 / 29 |
| esophagus | 9% | 0.35 | 131 / 1445 | 1% | 0.02 | 1 / 183 |
| prostate | 8% | 0.36 | 19 / 245 | 1% | 0.26 | 3 / 502 |
| uterus | 6% | 0.14 | 10 / 170 | 0% | 0.03 | 2 / 459 |
| adipose | 4% | 0.22 | 53 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 4% | 0.27 | 55 / 1335 | 0% | 0 | 0 / 0 |
| pancreas | 2% | 0.06 | 8 / 328 | 1% | 0.02 | 2 / 178 |
| skin | 2% | 0.06 | 38 / 1809 | 0% | 0.13 | 2 / 472 |
| adrenal gland | 2% | 0.07 | 5 / 258 | 0% | 0.01 | 1 / 230 |
| brain | 2% | 0.04 | 49 / 2642 | 0% | 0 | 0 / 705 |
| ovary | 1% | 0.02 | 2 / 180 | 0% | 0.03 | 1 / 430 |
| muscle | 1% | 0.03 | 10 / 803 | 0% | 0 | 0 / 0 |
| heart | 1% | 0.03 | 9 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006955 | Biological process | immune response |
| GO_0002377 | Biological process | immunoglobulin production |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005576 | Cellular component | extracellular region |
| Gene name | VPREB1 |
| Protein name | Immunoglobulin iota chain (CD179 antigen-like family member A) (Protein VPreB1) (V(pre)B protein) (VpreB protein) (CD antigen CD179a) V-set pre-B cell surrogate light chain 1 |
| Synonyms | VPREB |
| Description | FUNCTION: Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation. |
| Accessions | ENST00000302273.2 P12018 F8W8C9 ENST00000403807.4 |
