CRELD2 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
plasma cell	19 studies	49% ± 18%	Explore
natural killer cell	12 studies	19% ± 4%	Explore
plasmablast	11 studies	50% ± 21%	Explore
IgG plasma cell	9 studies	32% ± 14%	Explore
fibroblast	8 studies	24% ± 13%	Explore
IgA plasma cell	8 studies	38% ± 14%	Explore
ciliated cell	7 studies	26% ± 9%	Explore
CD8-positive, alpha-beta T cell	7 studies	20% ± 4%	Explore
epithelial cell	7 studies	32% ± 14%	Explore
CD16-negative, CD56-bright natural killer cell, human	6 studies	18% ± 3%	Explore
CD16-positive, CD56-dim natural killer cell, human	6 studies	18% ± 2%	Explore
endothelial cell	6 studies	22% ± 10%	Explore
plasmacytoid dendritic cell	6 studies	23% ± 6%	Explore
goblet cell	5 studies	22% ± 5%	Explore
pancreatic A cell	3 studies	34% ± 9%	Explore
type B pancreatic cell	3 studies	40% ± 4%	Explore
conventional dendritic cell	3 studies	28% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	19% ± 3%	Explore
hematopoietic precursor cell	3 studies	22% ± 4%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	3 studies	16% ± 0%	Explore
B cell	3 studies	21% ± 5%	Explore
adventitial cell	3 studies	19% ± 5%	Explore
innate lymphoid cell	3 studies	16% ± 1%	Explore
IgM plasma cell	3 studies	36% ± 11%	Explore
macrophage	3 studies	23% ± 3%	Explore
dendritic cell	3 studies	33% ± 5%	Explore
connective tissue cell	3 studies	30% ± 12%	Explore
gamma-delta T cell	3 studies	21% ± 6%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
lung	5 studies	23% ± 7%	Explore
intestine	4 studies	24% ± 8%	Explore
pancreas	3 studies	34% ± 6%	Explore
peripheral blood	3 studies	18% ± 2%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	100%	4220.87	328 / 328	100%	28.12	178 / 178
esophagus	100%	1611.76	1444 / 1445	100%	22.94	183 / 183
uterus	100%	1884.39	170 / 170	100%	35.50	458 / 459
stomach	100%	2283.79	359 / 359	100%	25.03	285 / 286
liver	100%	3790.51	226 / 226	100%	30.60	404 / 406
lung	100%	2299.71	576 / 578	100%	33.70	1151 / 1155
intestine	100%	1815.36	966 / 966	99%	27.42	522 / 527
prostate	100%	2122.48	244 / 245	99%	45.04	499 / 502
brain	99%	1302.49	2615 / 2642	100%	22.89	705 / 705
skin	100%	1603.74	1800 / 1809	99%	35.12	469 / 472
thymus	100%	5264.96	653 / 653	99%	34.58	598 / 605
breast	100%	1745.78	459 / 459	98%	28.59	1101 / 1118
bladder	100%	1960.43	21 / 21	98%	27.65	496 / 504
kidney	100%	1684.97	89 / 89	96%	15.73	865 / 901
adrenal gland	100%	1831.57	258 / 258	93%	24.17	214 / 230
ovary	100%	1581.24	180 / 180	92%	13.03	394 / 430
adipose	100%	1750.27	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	31.54	29 / 29
spleen	100%	2805.89	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	27.14	45 / 45
ureter	0%	0	0 / 0	100%	13.05	1 / 1
blood vessel	100%	1858.01	1330 / 1335	0%	0	0 / 0
heart	98%	1431.07	845 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	96%	19.39	77 / 80
muscle	90%	661.95	724 / 803	0%	0	0 / 0
peripheral blood	85%	1152.59	790 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0