PLAAT1 | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte precursor cell	9 studies	37% ± 16%	Explore
retinal cone cell	6 studies	44% ± 23%	Explore
GABAergic neuron	3 studies	21% ± 1%	Explore
glutamatergic neuron	3 studies	31% ± 3%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of PLAAT1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	95%	159.22	623 / 653	94%	8.94	569 / 605
brain	89%	211.16	2343 / 2642	95%	20.99	673 / 705
adrenal gland	95%	110.48	246 / 258	70%	6.57	162 / 230
esophagus	69%	117.70	990 / 1445	52%	4.43	96 / 183
breast	37%	26.87	170 / 459	68%	8.12	760 / 1118
skin	64%	91.81	1165 / 1809	37%	3.68	176 / 472
muscle	100%	1001.87	803 / 803	0%	0	0 / 0
ovary	6%	2.93	10 / 180	93%	9.83	402 / 430
heart	93%	249.80	798 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	74%	6.82	59 / 80
uterus	12%	10.82	21 / 170	61%	8.65	279 / 459
tonsil	0%	0	0 / 0	69%	8.65	31 / 45
lung	1%	0.83	6 / 578	59%	7.83	687 / 1155
kidney	21%	11.16	19 / 89	27%	1.34	246 / 901
stomach	25%	15.62	90 / 359	16%	0.73	46 / 286
bladder	5%	2.29	1 / 21	26%	2.39	129 / 504
intestine	16%	8.65	151 / 966	14%	0.83	74 / 527
pancreas	3%	1.60	11 / 328	14%	1.41	25 / 178
blood vessel	15%	10.03	198 / 1335	0%	0	0 / 0
adipose	14%	9.13	170 / 1204	0%	0	0 / 0
peripheral blood	8%	5.10	76 / 929	0%	0	0 / 0
prostate	4%	3.97	9 / 245	1%	0.07	7 / 502
liver	0%	0.48	1 / 226	4%	0.22	15 / 406
lymph node	0%	0	0 / 0	3%	0.10	1 / 29
spleen	3%	1.30	7 / 241	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0016042	Biological process	lipid catabolic process
GO_1903008	Biological process	organelle disassembly
GO_0046470	Biological process	phosphatidylcholine metabolic process
GO_0070306	Biological process	lens fiber cell differentiation
GO_0070292	Biological process	N-acylphosphatidylethanolamine metabolic process
GO_0005641	Cellular component	nuclear envelope lumen
GO_0016020	Cellular component	membrane
GO_0005739	Cellular component	mitochondrion
GO_0005764	Cellular component	lysosome
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0008970	Molecular function	phospholipase A1 activity
GO_0008374	Molecular function	O-acyltransferase activity
GO_0052739	Molecular function	phosphatidylserine 1-acylhydrolase activity
GO_0052740	Molecular function	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GO_0004623	Molecular function	phospholipase A2 activity
GO_0016410	Molecular function	N-acyltransferase activity
GO_0005515	Molecular function	protein binding

Gene name	PLAAT1
Protein name	Phospholipase A and acyltransferase 1 (EC 2.3.1.-) (EC 3.1.1.32) (EC 3.1.1.4) (HRAS-like suppressor 1) (HRSL1) (Phospholipid-metabolizing enzyme A-C1) Phospholipase A and acyltransferase 1
Synonyms	HRASLS
Description	FUNCTION: Exhibits both phospholipase A1/2 and acyltransferase activities . Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids . Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid . Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N-acylphosphatidylethanolamine (NAPE) which serves as precursor for N-acylethanolamines (NAEs) . .
Accessions	ENST00000416012.1 H7C3Y1 ENST00000650797.1 [Q9HDD0-2] Q9HDD0 ENST00000264735.4 [Q9HDD0-1]

PLAAT1 report