RNF13 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0046330Biological processpositive regulation of JNK cascade
GO_0051865Biological processprotein autoubiquitination
GO_0006511Biological processubiquitin-dependent protein catabolic process
GO_0051640Biological processorganelle localization
GO_0031902Cellular componentlate endosome membrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005654Cellular componentnucleoplasm
GO_0005637Cellular componentnuclear inner membrane
GO_0005783Cellular componentendoplasmic reticulum
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0005768Cellular componentendosome
GO_0005765Cellular componentlysosomal membrane
GO_0061630Molecular functionubiquitin protein ligase activity
GO_0008432Molecular functionJUN kinase binding
GO_0046872Molecular functionmetal ion binding
GO_0004842Molecular functionubiquitin-protein transferase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameRNF13
Protein nameRING-type E3 ubiquitin transferase (EC 2.3.2.27)
Ring finger protein 13
E3 ubiquitin-protein ligase RNF13 (EC 2.3.2.27) (RING finger protein 13)
SynonymsRZF
DescriptionFUNCTION: E3 ubiquitin-protein ligase that regulates cell proliferation . Involved in apoptosis regulation . Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA . Also involved in protein trafficking and localization . .

AccessionsF8WEX6
C9JYN7
ENST00000490631.5
ENST00000392894.8 [O43567-1]
ENST00000468648.5
C9JYY4
ENST00000474348.5
ENST00000459632.5
C9IY58
ENST00000482083.7
ENST00000466795.5
ENST00000467977.5
C9JRV0
C9JCY0
C9JU37
F8WDJ5
ENST00000344229.7 [O43567-1]
ENST00000361785.10 [O43567-2]
H7C5Q6
ENST00000468289.1
O43567
C9J383
ENST00000491086.5
C9J8T4
ENST00000467996.1
ENST00000466478.5
ENST00000470151.5
C9J7B4