ZP2 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of ZP2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	61%	3.38	201 / 328	1%	0.03	2 / 178
thymus	52%	4.93	342 / 653	0%	0	0 / 605
lung	50%	3.78	289 / 578	1%	0.22	14 / 1155
uterus	46%	3.77	79 / 170	1%	0.04	6 / 459
intestine	39%	10.79	381 / 966	7%	0.14	35 / 527
kidney	42%	4.38	37 / 89	0%	0	0 / 901
breast	33%	2.93	153 / 459	3%	0.57	38 / 1118
brain	34%	733.45	902 / 2642	0%	0.00	1 / 705
ovary	34%	19.90	61 / 180	0%	0.10	1 / 430
prostate	33%	2.31	81 / 245	0%	0.01	2 / 502
skin	25%	1.72	455 / 1809	0%	0.00	1 / 472
adipose	25%	1.60	295 / 1204	0%	0	0 / 0
bladder	19%	1.00	4 / 21	2%	0.04	10 / 504
stomach	11%	0.52	38 / 359	6%	0.11	18 / 286
peripheral blood	14%	1.31	129 / 929	0%	0	0 / 0
esophagus	12%	0.77	168 / 1445	2%	0.03	3 / 183
spleen	9%	0.58	22 / 241	0%	0	0 / 0
liver	9%	0.44	20 / 226	0%	0	0 / 406
muscle	8%	0.42	64 / 803	0%	0	0 / 0
blood vessel	7%	0.37	89 / 1335	0%	0	0 / 0
adrenal gland	5%	1.88	13 / 258	0%	0	0 / 230
heart	4%	0.21	32 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007339	Biological process	binding of sperm to zona pellucida
GO_0060046	Biological process	regulation of acrosome reaction
GO_0060468	Biological process	prevention of polyspermy
GO_0035805	Cellular component	egg coat
GO_0005783	Cellular component	endoplasmic reticulum
GO_0005576	Cellular component	extracellular region
GO_0062023	Cellular component	collagen-containing extracellular matrix
GO_0005886	Cellular component	plasma membrane
GO_0005771	Cellular component	multivesicular body
GO_0015026	Molecular function	coreceptor activity
GO_0035804	Molecular function	structural constituent of egg coat
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding
GO_0032190	Molecular function	acrosin binding

Gene name	ZP2
Protein name	Zona pellucida sperm-binding protein 2 (Zona pellucida glycoprotein 2) (Zp-2) (Zona pellucida protein A) [Cleaved into: Processed zona pellucida sperm-binding protein 2]
Synonyms	ZPA
Description	FUNCTION: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy . The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP2 may act as a secondary sperm receptor . .
Accessions	Q05996 ENST00000574091.6 [Q05996-1] ENST00000574002.1 [Q05996-1] ENST00000638300.1 [Q05996-1] ENST00000640487.3 [Q05996-2]

ZP2 report