COPG2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0072384Biological processorganelle transport along microtubule
GO_0006886Biological processintracellular protein transport
GO_0006888Biological processendoplasmic reticulum to Golgi vesicle-mediated transport
GO_0006890Biological processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO_0006891Biological processintra-Golgi vesicle-mediated transport
GO_0009306Biological processprotein secretion
GO_0000139Cellular componentGolgi membrane
GO_0030126Cellular componentCOPI vesicle coat
GO_0005783Cellular componentendoplasmic reticulum
GO_0005829Cellular componentcytosol
GO_0030426Cellular componentgrowth cone
GO_0005793Cellular componentendoplasmic reticulum-Golgi intermediate compartment
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0030133Cellular componenttransport vesicle
GO_0005198Molecular functionstructural molecule activity

IV. Literature review

[source]
Gene nameCOPG2
Protein nameCOPG2
Coatomer subunit gamma-2 (Gamma-2-coat protein) (Gamma-2-COP)
Synonyms
DescriptionFUNCTION: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity). .

AccessionsENST00000425248.5 [Q9UBF2-1]
Q9UBF2
ENST00000330992.8 [Q9UBF2-2]
Q96PK0