Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| fibroblast | 6 studies | 26% ± 4% | |
| myofibroblast cell | 4 studies | 22% ± 5% | |
| GABAergic neuron | 4 studies | 37% ± 13% | |
| astrocyte | 4 studies | 26% ± 6% | |
| neuron | 3 studies | 25% ± 7% | |
| endothelial cell | 3 studies | 21% ± 4% | |
| pericyte | 3 studies | 21% ± 6% | |
| ciliated cell | 3 studies | 24% ± 4% | |
| epithelial cell | 3 studies | 29% ± 11% | |
| glutamatergic neuron | 3 studies | 53% ± 8% | |
| oligodendrocyte precursor cell | 3 studies | 26% ± 4% | |
| connective tissue cell | 3 studies | 32% ± 11% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 36% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 1327.92 | 245 / 245 | 100% | 20.96 | 501 / 502 |
| ovary | 100% | 1641.93 | 180 / 180 | 100% | 15.47 | 429 / 430 |
| brain | 100% | 1706.92 | 2632 / 2642 | 100% | 28.59 | 704 / 705 |
| breast | 100% | 934.17 | 459 / 459 | 99% | 13.83 | 1104 / 1118 |
| thymus | 100% | 1433.17 | 653 / 653 | 99% | 13.37 | 597 / 605 |
| lung | 99% | 1019.01 | 573 / 578 | 99% | 12.11 | 1141 / 1155 |
| bladder | 100% | 1140.14 | 21 / 21 | 97% | 12.42 | 491 / 504 |
| adrenal gland | 100% | 2730.07 | 258 / 258 | 97% | 20.14 | 223 / 230 |
| kidney | 100% | 1157.56 | 89 / 89 | 97% | 12.49 | 872 / 901 |
| pancreas | 99% | 709.41 | 324 / 328 | 98% | 11.99 | 174 / 178 |
| uterus | 100% | 1735.92 | 170 / 170 | 94% | 15.31 | 431 / 459 |
| intestine | 99% | 1199.57 | 961 / 966 | 94% | 9.41 | 496 / 527 |
| esophagus | 96% | 1209.58 | 1380 / 1445 | 98% | 11.98 | 179 / 183 |
| skin | 97% | 1181.38 | 1746 / 1809 | 97% | 26.25 | 456 / 472 |
| stomach | 99% | 841.04 | 357 / 359 | 92% | 9.19 | 264 / 286 |
| liver | 100% | 909.51 | 226 / 226 | 90% | 7.22 | 365 / 406 |
| spleen | 100% | 822.96 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 5.84 | 1 / 1 |
| blood vessel | 100% | 1379.27 | 1329 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 100% | 989.97 | 1198 / 1204 | 0% | 0 | 0 / 0 |
| heart | 96% | 735.41 | 825 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 93% | 9.82 | 42 / 45 |
| eye | 0% | 0 | 0 / 0 | 88% | 11.05 | 70 / 80 |
| muscle | 80% | 331.91 | 641 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 72% | 5.23 | 21 / 29 |
| peripheral blood | 20% | 324.20 | 186 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0015012 | Biological process | heparan sulfate proteoglycan biosynthetic process |
| GO_0006044 | Biological process | N-acetylglucosamine metabolic process |
| GO_0019276 | Biological process | UDP-N-acetylgalactosamine metabolic process |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0030145 | Molecular function | manganese ion binding |
| GO_0035248 | Molecular function | alpha-1,4-N-acetylgalactosaminyltransferase activity |
| GO_0047237 | Molecular function | glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0001888 | Molecular function | glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity |
| GO_0005539 | Molecular function | glycosaminoglycan binding |
| Gene name | EXTL2 |
| Protein name | EXTL2 Exostoses (Multiple)-like 2 Exostosin like glycosyltransferase 2 Exostoses (Multiple)-like 2, isoform CRA_b (cDNA FLJ39595 fis, clone SKNSH2001931, highly similar to Exostoses) EXTL2 protein Exostosin-like 2 (EC 2.4.1.223) (Alpha-1,4-N-acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) [Cleaved into: Processed exostosin-like 2] |
| Synonyms | hCG_32848 EXTR2 |
| Description | FUNCTION: Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains. . |
| Accessions | Q49A43 ENST00000370114.8 ENST00000416479.1 ENST00000535414.5 Q05DH5 Q8N8F1 Q8IYF4 ENST00000370113.7 Q9UBQ6 O00245 C9JEG3 C9IYF5 F5GZK1 ENST00000450240.2 |