GDPD3 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GDPD3 at tissue level.

III. Associated gene sets

GO_0034638Biological processphosphatidylcholine catabolic process
GO_0070291Biological processN-acylethanolamine metabolic process
GO_0046475Biological processglycerophospholipid catabolic process
GO_0070062Cellular componentextracellular exosome
GO_0005783Cellular componentendoplasmic reticulum
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0004622Molecular functionlysophospholipase activity
GO_0046872Molecular functionmetal ion binding
GO_0008081Molecular functionphosphoric diester hydrolase activity

IV. Literature review

[source]
Gene nameGDPD3
Protein nameLysophospholipase D GDPD3 (EC 3.1.4.-) (Glycerophosphodiester phosphodiesterase 7) (Glycerophosphodiester phosphodiesterase domain-containing protein 3)
Glycerophosphodiester phosphodiesterase domain containing 3
SynonymsGDE7
DescriptionFUNCTION: Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines . Shows a preference for 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF), lysophosphatidylcholine (lyso-PC) and N-acylethanolamine lysophospholipids . Does not display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine. .

AccessionsQ7L5L3
ENST00000566613.1
H3BPX3
ENST00000406256.8 [Q7L5L3-2]
ENST00000566434.5
H3BMN9