PSMF1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
CD8-positive, alpha-beta T cell	18 studies	24% ± 5%	Explore
CD4-positive, alpha-beta T cell	17 studies	24% ± 5%	Explore
natural killer cell	17 studies	24% ± 6%	Explore
regulatory T cell	16 studies	26% ± 6%	Explore
endothelial cell	15 studies	27% ± 10%	Explore
macrophage	14 studies	23% ± 7%	Explore
B cell	14 studies	23% ± 5%	Explore
non-classical monocyte	13 studies	29% ± 11%	Explore
fibroblast	12 studies	26% ± 9%	Explore
pericyte	12 studies	23% ± 6%	Explore
conventional dendritic cell	11 studies	29% ± 14%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	25% ± 5%	Explore
memory B cell	11 studies	22% ± 5%	Explore
gamma-delta T cell	11 studies	26% ± 9%	Explore
T cell	10 studies	22% ± 5%	Explore
classical monocyte	10 studies	26% ± 9%	Explore
mature NK T cell	10 studies	25% ± 7%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	10 studies	22% ± 6%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	10 studies	24% ± 4%	Explore
naive B cell	10 studies	21% ± 4%	Explore
erythrocyte	9 studies	38% ± 17%	Explore
CD16-negative, CD56-bright natural killer cell, human	9 studies	25% ± 5%	Explore
mucosal invariant T cell	9 studies	24% ± 5%	Explore
monocyte	9 studies	19% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	8 studies	23% ± 4%	Explore
epithelial cell	8 studies	37% ± 16%	Explore
endothelial cell of lymphatic vessel	8 studies	22% ± 5%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	26% ± 7%	Explore
dendritic cell	7 studies	32% ± 18%	Explore
ciliated cell	7 studies	25% ± 7%	Explore
abnormal cell	7 studies	32% ± 15%	Explore
plasmacytoid dendritic cell	7 studies	25% ± 6%	Explore
plasma cell	6 studies	28% ± 10%	Explore
smooth muscle cell	6 studies	27% ± 7%	Explore
myeloid cell	6 studies	21% ± 8%	Explore
plasmablast	5 studies	43% ± 19%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	28% ± 3%	Explore
erythroblast	5 studies	32% ± 18%	Explore
hematopoietic stem cell	5 studies	23% ± 7%	Explore
connective tissue cell	5 studies	25% ± 5%	Explore
myofibroblast cell	5 studies	28% ± 8%	Explore
basal cell	5 studies	30% ± 11%	Explore
astrocyte	5 studies	30% ± 7%	Explore
T follicular helper cell	5 studies	21% ± 3%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	26% ± 7%	Explore
endothelial cell of vascular tree	5 studies	20% ± 4%	Explore
oligodendrocyte precursor cell	5 studies	27% ± 8%	Explore
goblet cell	5 studies	27% ± 10%	Explore
neuron	5 studies	40% ± 22%	Explore
oligodendrocyte	5 studies	24% ± 5%	Explore
hematopoietic precursor cell	4 studies	31% ± 10%	Explore
pancreatic A cell	4 studies	39% ± 14%	Explore
exhausted T cell	4 studies	29% ± 4%	Explore
microglial cell	4 studies	23% ± 5%	Explore
lymphocyte	4 studies	21% ± 4%	Explore
type I pneumocyte	4 studies	23% ± 5%	Explore
type II pneumocyte	4 studies	24% ± 10%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	29% ± 7%	Explore
glutamatergic neuron	4 studies	45% ± 17%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	28% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	21% ± 7%	Explore
type B pancreatic cell	3 studies	46% ± 11%	Explore
precursor B cell	3 studies	24% ± 5%	Explore
capillary endothelial cell	3 studies	18% ± 4%	Explore
immature B cell	3 studies	23% ± 4%	Explore
GABAergic neuron	3 studies	44% ± 6%	Explore
pancreatic ductal cell	3 studies	42% ± 19%	Explore
enteroendocrine cell	3 studies	29% ± 15%	Explore
group 3 innate lymphoid cell	3 studies	24% ± 7%	Explore
transit amplifying cell	3 studies	22% ± 5%	Explore
T-helper 1 cell	3 studies	23% ± 4%	Explore
innate lymphoid cell	3 studies	23% ± 4%	Explore
double negative thymocyte	3 studies	35% ± 9%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	13 studies	25% ± 5%	Explore
lung	9 studies	22% ± 5%	Explore
brain	6 studies	34% ± 10%	Explore
lymph node	5 studies	23% ± 10%	Explore
liver	4 studies	37% ± 21%	Explore
pancreas	3 studies	46% ± 5%	Explore
eye	3 studies	25% ± 2%	Explore
intestine	3 studies	25% ± 11%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	100%	5955.52	21 / 21	100%	46.53	504 / 504
esophagus	100%	5483.46	1445 / 1445	100%	47.92	183 / 183
intestine	100%	5595.30	966 / 966	100%	51.08	527 / 527
kidney	100%	4850.20	89 / 89	100%	43.04	901 / 901
liver	100%	4555.95	226 / 226	100%	42.23	406 / 406
ovary	100%	5817.37	180 / 180	100%	54.69	430 / 430
pancreas	100%	4172.10	328 / 328	100%	37.23	178 / 178
prostate	100%	4947.79	245 / 245	100%	43.13	502 / 502
skin	100%	5945.53	1809 / 1809	100%	53.97	472 / 472
stomach	100%	4724.56	359 / 359	100%	50.60	286 / 286
thymus	100%	5384.16	653 / 653	100%	46.82	605 / 605
lung	100%	5716.46	578 / 578	100%	45.34	1154 / 1155
brain	100%	4343.03	2639 / 2642	100%	49.84	705 / 705
uterus	100%	5656.40	170 / 170	100%	44.15	458 / 459
breast	100%	6054.16	459 / 459	100%	48.76	1114 / 1118
adrenal gland	100%	4994.53	258 / 258	99%	32.90	228 / 230
adipose	100%	6286.36	1204 / 1204	0%	0	0 / 0
blood vessel	100%	6731.12	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	50.86	80 / 80
lymph node	0%	0	0 / 0	100%	47.68	29 / 29
muscle	100%	7580.89	803 / 803	0%	0	0 / 0
peripheral blood	100%	6852.85	929 / 929	0%	0	0 / 0
spleen	100%	4964.29	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	43.18	45 / 45
ureter	0%	0	0 / 0	100%	17.72	1 / 1
heart	98%	4361.39	846 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006511	Biological process	ubiquitin-dependent protein catabolic process
GO_1901799	Biological process	negative regulation of proteasomal protein catabolic process
GO_0043161	Biological process	proteasome-mediated ubiquitin-dependent protein catabolic process
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005783	Cellular component	endoplasmic reticulum
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0016020	Cellular component	membrane
GO_0005839	Cellular component	proteasome core complex
GO_0046982	Molecular function	protein heterodimerization activity
GO_0042803	Molecular function	protein homodimerization activity
GO_0004866	Molecular function	endopeptidase inhibitor activity
GO_0070628	Molecular function	proteasome binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	PSMF1
Protein name	Proteasome inhibitor PI31 subunit Proteasome inhibitor PI31 subunit (hPI31) Proteasome inhibitor subunit 1
Synonyms
Description	FUNCTION: Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28. . FUNCTION: Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28. .
Accessions	ENST00000333082.7 H0Y555 Q5QPM7 ENST00000435720.5 ENST00000652336.1 F5H4Z3 Q5QPM9 ENST00000381898.5 ENST00000335877.11 ENST00000381899.8 ENST00000246015.8 Q92530

PSMF1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review