BNIP1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of BNIP1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of BNIP1 at tissue level.

III. Associated gene sets

GO_0006890Biological processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO_0019722Biological processcalcium-mediated signaling
GO_0007029Biological processendoplasmic reticulum organization
GO_0016320Biological processendoplasmic reticulum membrane fusion
GO_0043066Biological processnegative regulation of apoptotic process
GO_0097194Biological processexecution phase of apoptosis
GO_0006915Biological processapoptotic process
GO_0140208Biological processapoptotic process in response to mitochondrial fragmentation
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0031966Cellular componentmitochondrial membrane
GO_0005635Cellular componentnuclear envelope
GO_0005783Cellular componentendoplasmic reticulum
GO_0005737Cellular componentcytoplasm
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0005741Cellular componentmitochondrial outer membrane
GO_0031201Cellular componentSNARE complex
GO_0048763Molecular functioncalcium-induced calcium release activity
GO_0005484Molecular functionSNAP receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameBNIP1
Protein nameVesicle transport protein SEC20 (BCL2/adenovirus E1B 19 kDa protein-interacting protein 1) (Transformation-related gene 8 protein) (TRG-8)
BCL2 interacting protein 1
SynonymsNIP1
SEC20L
TRG8
DescriptionFUNCTION: As part of a SNARE complex may be involved in endoplasmic reticulum membranes fusion and be required for the maintenance of endoplasmic reticulum organization . Also plays a role in apoptosis . It is for instance required for endoplasmic reticulum stress-induced apoptosis . As a substrate of RNF185 interacting with SQSTM1, might also be involved in mitochondrial autophagy (Probable). .

AccessionsENST00000352523.10 [Q12981-3]
ENST00000393770.4 [Q12981-2]
Q12981
ENST00000519459.2
H0YBK7
ENST00000351486.10 [Q12981-4]
ENST00000231668.13 [Q12981-1]