Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 11 studies | 28% ± 11% | |
| astrocyte | 10 studies | 26% ± 12% | |
| ciliated cell | 8 studies | 21% ± 3% | |
| non-classical monocyte | 7 studies | 27% ± 16% | |
| retinal rod cell | 7 studies | 33% ± 8% | |
| macrophage | 7 studies | 30% ± 9% | |
| microglial cell | 7 studies | 25% ± 7% | |
| dendritic cell | 7 studies | 25% ± 11% | |
| retinal cone cell | 6 studies | 43% ± 13% | |
| oligodendrocyte | 6 studies | 24% ± 8% | |
| myeloid cell | 5 studies | 23% ± 4% | |
| epithelial cell | 5 studies | 31% ± 9% | |
| GABAergic neuron | 5 studies | 38% ± 19% | |
| monocyte | 5 studies | 25% ± 10% | |
| adipocyte | 4 studies | 20% ± 2% | |
| retina horizontal cell | 4 studies | 20% ± 4% | |
| hepatocyte | 4 studies | 43% ± 13% | |
| type I pneumocyte | 4 studies | 21% ± 4% | |
| type II pneumocyte | 4 studies | 21% ± 5% | |
| glutamatergic neuron | 4 studies | 48% ± 22% | |
| oligodendrocyte precursor cell | 4 studies | 26% ± 8% | |
| endothelial cell of lymphatic vessel | 4 studies | 32% ± 10% | |
| fibroblast | 4 studies | 20% ± 6% | |
| interneuron | 4 studies | 38% ± 22% | |
| classical monocyte | 3 studies | 29% ± 9% | |
| retinal pigment epithelial cell | 3 studies | 29% ± 10% | |
| cardiac muscle cell | 3 studies | 19% ± 2% | |
| abnormal cell | 3 studies | 31% ± 14% | |
| ependymal cell | 3 studies | 27% ± 13% | |
| club cell | 3 studies | 18% ± 2% | |
| lymphocyte | 3 studies | 28% ± 7% | |
| basal cell | 3 studies | 25% ± 4% | |
| epithelial cell of proximal tubule | 3 studies | 25% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 8139.14 | 2642 / 2642 | 100% | 47.06 | 705 / 705 |
| breast | 100% | 3955.07 | 459 / 459 | 100% | 35.98 | 1118 / 1118 |
| esophagus | 100% | 4403.11 | 1445 / 1445 | 100% | 26.84 | 183 / 183 |
| intestine | 100% | 4687.21 | 966 / 966 | 100% | 27.75 | 527 / 527 |
| kidney | 100% | 6234.09 | 89 / 89 | 100% | 37.14 | 901 / 901 |
| prostate | 100% | 4041.29 | 245 / 245 | 100% | 34.43 | 502 / 502 |
| stomach | 100% | 3707.21 | 359 / 359 | 100% | 27.54 | 286 / 286 |
| thymus | 100% | 5629.80 | 653 / 653 | 100% | 32.64 | 605 / 605 |
| liver | 100% | 6309.20 | 226 / 226 | 100% | 31.73 | 405 / 406 |
| pancreas | 100% | 3005.60 | 327 / 328 | 100% | 22.05 | 178 / 178 |
| bladder | 100% | 3572.10 | 21 / 21 | 100% | 28.31 | 502 / 504 |
| skin | 100% | 5729.08 | 1809 / 1809 | 100% | 33.15 | 470 / 472 |
| uterus | 100% | 2966.67 | 170 / 170 | 99% | 23.95 | 456 / 459 |
| lung | 100% | 4861.69 | 577 / 578 | 99% | 27.09 | 1149 / 1155 |
| ovary | 100% | 2743.97 | 180 / 180 | 98% | 22.09 | 420 / 430 |
| adrenal gland | 100% | 5146.67 | 258 / 258 | 94% | 12.76 | 217 / 230 |
| adipose | 100% | 4200.90 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 45.74 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 31.90 | 29 / 29 |
| muscle | 100% | 9293.85 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 5018.64 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 28.59 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 21.78 | 1 / 1 |
| blood vessel | 99% | 2706.06 | 1328 / 1335 | 0% | 0 | 0 / 0 |
| heart | 96% | 4310.32 | 830 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 94% | 4136.89 | 876 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006654 | Biological process | phosphatidic acid biosynthetic process |
| GO_0008654 | Biological process | phospholipid biosynthetic process |
| GO_0016024 | Biological process | CDP-diacylglycerol biosynthetic process |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0012505 | Cellular component | endomembrane system |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005635 | Cellular component | nuclear envelope |
| GO_0016020 | Cellular component | membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0003841 | Molecular function | 1-acylglycerol-3-phosphate O-acyltransferase activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | AGPAT3 |
| Protein name | 1-acylglycerol-3-phosphate O-acyltransferase 3, isoform CRA_b (cDNA FLJ23720 fis, clone HEP13757) 1-acylglycerol-3-phosphate O-acyltransferase 3 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 3) (1-AGP acyltransferase 3) (1-AGPAT 3) (Lysophosphatidic acid acyltransferase gamma) (LPAAT-gamma) |
| Synonyms | LPAAT3 hCG_2010443 UNQ759/PRO1490 |
| Description | FUNCTION: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone . Acts on LPA containing saturated or unsaturated fatty acids C16:0-C20:4 at the sn-1 position using C18:1, C20:4 or C18:2-CoA as the acyl donor . Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18:1 or C20:4-CoA . Has a preference for arachidonoyl-CoA as a donor (By similarity). Has also a modest lysophosphatidylinositol acyltransferase (LPIAT) activity, converts lysophosphatidylinositol (LPI) into phosphatidylinositol (By similarity). . |
| Accessions | ENST00000398058.5 [Q9NRZ7-1] ENST00000291572.13 [Q9NRZ7-1] ENST00000398061.5 [Q9NRZ7-1] C9JK35 ENST00000448845.1 Q9NRZ7 ENST00000398063.6 [Q9NRZ7-1] ENST00000422850.5 C9JL26 C9J184 ENST00000327505.6 [Q9NRZ7-1] ENST00000457068.5 ENST00000546158.1 [Q9NRZ7-1] ENST00000448287.5 Q8TEB0 C9JQX8 ENST00000445582.5 |