AGPAT3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006654Biological processphosphatidic acid biosynthetic process
GO_0008654Biological processphospholipid biosynthetic process
GO_0016024Biological processCDP-diacylglycerol biosynthetic process
GO_0000139Cellular componentGolgi membrane
GO_0012505Cellular componentendomembrane system
GO_0005783Cellular componentendoplasmic reticulum
GO_0005886Cellular componentplasma membrane
GO_0005635Cellular componentnuclear envelope
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0003841Molecular function1-acylglycerol-3-phosphate O-acyltransferase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameAGPAT3
Protein name1-acylglycerol-3-phosphate O-acyltransferase 3, isoform CRA_b (cDNA FLJ23720 fis, clone HEP13757)
1-acylglycerol-3-phosphate O-acyltransferase 3
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 3) (1-AGP acyltransferase 3) (1-AGPAT 3) (Lysophosphatidic acid acyltransferase gamma) (LPAAT-gamma)
SynonymsLPAAT3
hCG_2010443
UNQ759/PRO1490
DescriptionFUNCTION: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone . Acts on LPA containing saturated or unsaturated fatty acids C16:0-C20:4 at the sn-1 position using C18:1, C20:4 or C18:2-CoA as the acyl donor . Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18:1 or C20:4-CoA . Has a preference for arachidonoyl-CoA as a donor (By similarity). Has also a modest lysophosphatidylinositol acyltransferase (LPIAT) activity, converts lysophosphatidylinositol (LPI) into phosphatidylinositol (By similarity). .

AccessionsENST00000398058.5 [Q9NRZ7-1]
ENST00000291572.13 [Q9NRZ7-1]
ENST00000398061.5 [Q9NRZ7-1]
C9JK35
ENST00000448845.1
Q9NRZ7
ENST00000398063.6 [Q9NRZ7-1]
ENST00000422850.5
C9JL26
C9J184
ENST00000327505.6 [Q9NRZ7-1]
ENST00000457068.5
ENST00000546158.1 [Q9NRZ7-1]
ENST00000448287.5
Q8TEB0
C9JQX8
ENST00000445582.5